Purpose Osteochondral defects (ie, defects which affect both the articular cartilage and
underlying subchondral bone) are often associated with mechanical instability of the joint …

Cryopreservation has numerous practical applications in medicine, biotechnology,
agriculture, forestry, aquaculture and biodiversity conservation, with huge potentials for …

Background: Large osteochondral defects of the talus present a treatment challenge. Fresh
osteochondral allograft transplantation can be used for large lesions without the donor-site …

Настоящая книга посвящена вопросам возникновения, механизмам развития хрящевых
повреждений в коленном суставе, основным методам их клинического выявления и …

Autologous bone grafting represents the standard of care for treating bone defects but this
biomaterial is unreliable in older patients. The efficacy of an autograft can be traced back to …

The ability to isolate specific, viable cell populations from mixed ensembles with minimal
manipulation and within intra-operative time would provide significant advantages for …

Background Osteochondral allograft transplantation has a good clinical outcome, however,
there is still debate on optimization of allograft storage protocol. Storage temperature and …

Osteochondral lesions of the talus are being recognized as an increasingly common injury.
They are most commonly located postero-medially or antero-laterally, while centrally located …

Background: Osteochondral allografts are an increasingly popular treatment for the repair of
articular cartilage lesions. Current tissue bank protocols require bacteriological testing that …

Background: A major limitation of osteochondral allografts (OCA) is the deterioration of
cartilage health associated with cell death during prolonged storage. However, little is …