Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

Potassium ion (K+) channel activity is a major regulator of vascular muscle cell membrane
potential (E m) and is therefore an important determinant of vascular tone. There is growing …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

Potassium (K+) channels are usually predominant in the membranes of vascular smooth
muscle cells (SMCs). These channels play an important role in regulating the membrane …

Altered function of K+ channels associated with hypertension has been inferred from the
effects of K+ channel blockers on contraction of arterial smooth muscle cells (SMCs) and …

Different types of ATP-sensitive K+ (KATP) channels have been identified in cardiomyocytes,
vascular smooth muscle cells, pancreatic β-cells, neurons and mitochondria. Years before …

Background Endothelial dysfunction has been described in obesity. This study examines the
impact of visceral obesity on nitric oxide-independent relaxation in the human forearm …

Key points• Essential hypertension involves an electrical remodelling of vascular smooth
muscle cells (VSMCs), particularly relevant for K+ channels, as key determinants of resting …

Activation of Na+/H+ exchanger (NHE) may have an important role in ischemic cell death by
means of intracellular overload of Na+ and Ca2+. Recent evidence has suggested that …