The ultimate goal of radiation oncology is to eradicate tumours without toxicity to non-
malignant tissues. FLASH radiotherapy, or the delivery of ultra-high dose rates of radiation …

It is well known that radiation therapy causes lymphopenia in patients and that this is
correlated with a negative outcome. The mechanism is not well understood because …

Radiation-induced lymphopenia (RIL) is a frequent, and often considered unavoidable, side
effect of radiation therapy (RT), whether or not chemotherapy is included. However, in the …

Charged particle radiotherapy, mainly using protons and carbon ions, provides physical
characteristics allowing for a volume conformal irradiation and a reduction of the integral …

Purpose. Lymphopenia is a common side effect in patients treated with radiotherapy,
potentially caused by direct cell killing of circulating lymphocytes in the blood. To investigate …

Background We estimated the dose of circulating blood cells (CBCs) in patients with locally
advanced non-small cell lung cancer for predicting severe radiation-induced lymphopenia …

Purpose Radiation-induced lymphopenia has gained attention recently as the result of its
correlation with survival in a range of indications, particularly when combining radiation …

There is a rising interest in developing and utilizing arc delivery techniques with charged
particle beams, eg, proton, carbon or other ions, for clinical implementation. In this work …

Purpose To investigate the beam delivery time (BDT) reduction due to the improvement of
machine parameters for Hitachi synchrotron-based proton PBS system. Methods BDTs for …

Objective. Phantoms of the International Commission on Radiological Protection provide a
framework for standardized dosimetry. The modeling of internal blood vessels—essential to …