Therapeutic vaccines for HPV-associated malignancies
C Smalley Rumfield, N Roller, ST Pellom… - ImmunoTargets and …, 2020 - Taylor & Francis
Human papillomavirus (HPV)-related malignancies are responsible for almost all cases of
cervical cancer in women, and over 50% of all cases of head and neck carcinoma …
cervical cancer in women, and over 50% of all cases of head and neck carcinoma …
Methods to improve the immunogenicity of plasmid DNA vaccines
DNA vaccines have emerged as innovative approaches that have great potential to
overcome the limitations of current conventional vaccines. Plasmid DNA vaccines are often …
overcome the limitations of current conventional vaccines. Plasmid DNA vaccines are often …
Ready for repair? Gene editing enters the clinic for the treatment of human disease
MPT Ernst, M Broeders, P Herrero-Hernandez… - … Therapy Methods & …, 2020 - cell.com
We present an overview of clinical trials involving gene editing using clustered interspaced
short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription …
short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription …
Quantitative proteomics reveals a broad‐spectrum antiviral property of ivermectin, benefiting for COVID‐19 treatment
N Li, L Zhao, X Zhan - Journal of Cellular Physiology, 2021 - Wiley Online Library
Viruses such as human cytomegalovirus (HCMV), human papillomavirus (HPV), Epstein–
Barr virus (EBV), human immunodeficiency virus (HIV), and coronavirus (severe acute …
Barr virus (EBV), human immunodeficiency virus (HIV), and coronavirus (severe acute …
Flavonoids-based delivery systems towards cancer therapies
M Ferreira, D Costa, Â Sousa - Bioengineering, 2022 - mdpi.com
Cancer is the second leading cause of death worldwide. Cervical cancer, for instance, is
considered a major scourge in low-income countries. Its development is mostly associated …
considered a major scourge in low-income countries. Its development is mostly associated …
Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes
X Sun, P Fu, L Xie, S Chai, Q Xu… - International …, 2021 - spandidos-publications.com
Resveratrol is a representative polyphenol of diet‑derived putative cancer chemopreventive
agents, which have attracted increasing interest in the cancer chemoprevention community …
agents, which have attracted increasing interest in the cancer chemoprevention community …
In silico approaches: a way to unveil novel therapeutic drugs for cervical cancer management
Cervical cancer (CC) is the fourth most common pathology in women worldwide and
presents a high impact in developing countries due to limited financial resources as well as …
presents a high impact in developing countries due to limited financial resources as well as …
[HTML][HTML] Development and characterization of quercetin-loaded delivery systems for increasing its bioavailability in cervical cancer cells
M Ferreira, D Gomes, M Neto, LA Passarinha, D Costa… - Pharmaceutics, 2023 - mdpi.com
Quercetin is a natural flavonoid with high anticancer activity, especially for related-HPV
cancers such as cervical cancer. However, quercetin exhibits a reduced aqueous solubility …
cancers such as cervical cancer. However, quercetin exhibits a reduced aqueous solubility …
Brucine promotes apoptosis in cervical cancer cells (ME‐180) via suppression of inflammation and cell proliferation by regulating PI3K/AKT/mTOR signaling pathway
VD Seshadri - Environmental toxicology, 2021 - Wiley Online Library
Brucine are the main constituents of Strychnos nux‐vomica. Earlier reports have determined
brucine shows anti‐inflammatory, analgesic and excellent anti‐tumor drug. Even though its …
brucine shows anti‐inflammatory, analgesic and excellent anti‐tumor drug. Even though its …
Epigenetic and genetic keys to fight hpv-related cancers
V Folliero, F Dell'Annunziata, A Chianese, MV Morone… - Cancers, 2023 - mdpi.com
Simple Summary Human papillomavirus (HPV) infection is a highly prevalent sexually
transmitted disease globally. Although most HPV infections do not result in cancer, certain …
transmitted disease globally. Although most HPV infections do not result in cancer, certain …