Clinical aspects and outcomes in osteoarthritis

MT Duruöz, N Öz, DE Gürsoy, HH Gezer - Best Practice & Research …, 2023 - Elsevier
Osteoarthritis (OA) is the most prevalent type of arthritis worldwide, and its incidence
significantly increases with age. It commonly affects the knees, hips, spine, big toes, and …

[HTML][HTML] The association between comorbidities and disease activity in spondyloarthritis–A narrative review

P Bosch, SS Zhao, E Nikiphorou - Best Practice & Research Clinical …, 2023 - Elsevier
Comorbidities, including cardiovascular disease, osteoporosis, and depression, are more
prevalent in patients with spondyloarthritis (SpA) than in the general population. Clinical and …

Optimal Biologic Drugs for the Treatment of Ankylosing Spondylitis: Results from a Network Meta‐Analysis and Network Metaregression

Z Cao, J Guo, Q Li, Y Li, J Wu - BioMed Research International, 2022 - Wiley Online Library
Background. Ankylosing spondylitis (AS) is a common immune‐related systemic chronic
inflammatory osteoarthropathy. Previous studies have proven that biologic agents, including …

Deregulation of microRNA expression in monocytes and CD4+ T lymphocytes from patients with axial spondyloarthritis

O Fogel, A Bugge Tinggaard, M Fagny, N Sigrist… - Arthritis Research & …, 2019 - Springer
Abstract Background MicroRNAs (MiRs) play an important role in the pathogenesis of
chronic inflammatory diseases. This study is the first to investigate miR expression profiles in …

A contemporary view of the diagnosis of osteoporosis in patients with axial spondyloarthritis

MJ Lim, KY Kang - Frontiers in Medicine, 2020 - frontiersin.org
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that primarily affects the
axial joints. Altered bone metabolism associated with chronic inflammation leads to both …

Anti-Osteogenic Effect of Danshensu in Ankylosing Spondylitis: An in Vitro Study Based on Integrated Network Pharmacology

J Li, Z Chen, H Liao, Y Zhong, J Hua, M Su… - Frontiers in …, 2021 - frontiersin.org
Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by abnormal
bone metabolism, with few effective treatments available. Danshensu [3-(3, 4-dihydroxy …

Longitudinal association between trabecular bone loss and disease activity in axial spondyloarthritis: a 4-year prospective study

KY Kang, JH Ju, SH Park, YS Hong - The Journal of Rheumatology, 2020 - jrheum.org
Objective. To investigate whether trabecular bone loss is longitudinally associated with
disease activity measures in patientswith axial spondyloarthritis (axSpA). Methods. Data …

Measuring bone density in axial spondyloarthropathy: Time to turn things on their side?

G Fitzgerald, T Anachebe, K McCarroll… - International Journal of …, 2020 - Wiley Online Library
Aim Osteoporosis in axial spondyloarthropathy (axSpA) is difficult to accurately diagnose
due to osteoproliferation of the spine interfering with conventional (anteroposterior, AP) dual …

Tail suspension delays ectopic ossification in proteoglycan‑induced ankylosing spondylitis in mice via miR‑103/DKK1

Z Zhang, J Zeng, Y Li, Q Liao… - Experimental and …, 2021 - spandidos-publications.com
Ankylosing spondylitis (AS), characterized by inflammatory lesions and osteophyte
formation, is a common immune rheumatic disease affecting the sacroiliac and axial joints. A …

Evolving concepts of new bone formation in axial spondyloarthritis: insights from animal models and human studies

RJ Lories, N Haroon - Best Practice & Research Clinical Rheumatology, 2017 - Elsevier
New bone formation potentially leading to ankylosis of the sacroiliac joints and the spine is
the main type of structural damage to the skeleton that characterizes axial spondyloarthritis …