AMPK is an important kinase regulating energy homeostasis and also a key protein involved
in a variety of signal transduction pathways. It plays a vitally regulatory role in cellular …

Apart from being a safe, effective and globally affordable glucose-lowering agent for the
treatment of diabetes, metformin has earned much credit in recent years as a potential anti …

Many insects enter a dormant state termed diapause in anticipation of seasonal inhospitable
conditions. Insects drastically reduce their feeding during diapause. Their reduced nutrient …

Background Metformin, a medication for type 2 diabetes, has been linked to many non-
diabetes health benefits including increasing healthy lifespan. Previous work has only …

Calorie restriction (CR) can prolong the human lifespan, but enforcing long-term CR is
difficult. Therefore, a compound that reproduces the effect of CR without CR is needed. In …

Obesity caused by excessive fat accumulation in adipocytes is a growing global problem
and is a major contributing risk factor for many chronic metabolic diseases. There is …

In the context of the growing prevalence of type 2 diabetes (T2DM), control of postprandial
hyperglycemia is crucial for its prevention. Blood glucose levels are determined by various …

Metformin is a hypoglycemic agent used clinically in the treatment of type 2 diabetics. In
addition, metformin is being investigated as a potential geroprotector. Here, we investigated …

Insects are equipped with neurological, physiological, and behavioral tools to locate
potential food sources and assess their nutritional quality based on volatile and chemotactile …

Aging is a complex phenomenon caused by the time-dependent loss of cellular
homeodynamics and consequently of physiological organismal functions. This process is …