Streptococcus pneumoniae's Virulence and Host Immunity: Aging, Diagnostics, and Prevention

LRK Brooks, GI Mias - Frontiers in immunology, 2018 - frontiersin.org
Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection

M Masomian, Z Ahmad, L Ti Gew, CL Poh - Vaccines, 2020 - mdpi.com
Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million
deaths annually, especially in young children and the elderly. To date, at least 98 different …

[HTML][HTML] Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an …

PA Waight, NJ Andrews, SN Ladhani… - The Lancet infectious …, 2015 - thelancet.com
Background The 13-valent pneumococcal conjugate vaccine (PCV13) protects against key
serotypes that increased after routine immunisation with the seven-valent vaccine (PCV7) …

Macrolide Resistance in Streptococcus pneumoniae

MR Schroeder, DS Stephens - Frontiers in cellular and infection …, 2016 - frontiersin.org
Streptococcus pneumoniae is a common commensal and an opportunistic pathogen.
Suspected pneumococcal upper respiratory infections and pneumonia are often treated with …

The worldwide impact of the seven-valent pneumococcal conjugate vaccine

SP Fitzwater, A Chandran, M Santosham… - The Pediatric …, 2012 - journals.lww.com
Background: Pneumococcal conjugate vaccines (PCV) are emerging as one of the most
promising means to prevent pediatric disease. The 7-valent PCV (PCV-7) has been …

Decline in pneumococcal nasopharyngeal carriage of vaccine serotypes after the introduction of the 13-valent pneumococcal conjugate vaccine in children in Atlanta …

AP Desai, D Sharma, EK Crispell… - The Pediatric …, 2015 - journals.lww.com
Background: Streptococcus pneumoniae (SP) serotype distribution among nasopharyngeal
(NP) carriage isolates changed significantly after the introduction of the 7-valent …

Increase of Macrolide-Resistance in Streptococcus pneumoniae Strains After the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Lima, Peru

BE Gonzales, EH Mercado… - Frontiers in Cellular …, 2022 - frontiersin.org
Streptococcus pneumoniae upper respiratory infections and pneumonia are often treated
with macrolides, but recently macrolide resistance is becoming an increasingly important …

Streptococcus pneumoniae Otitis Media Pathogenesis and How It Informs Our Understanding of Vaccine Strategies

C Bergenfelz, AP Hakansson - Current otorhinolaryngology reports, 2017 - Springer
Abstract Purpose of Review This study aimed to review the literature regarding the
mechanisms of transition from asymptomatic colonization to induction of otitis media and …

Pneumococcal vaccines: host interactions, population dynamics, and design principles

NJ Croucher, A Løchen… - Annual review of …, 2018 - annualreviews.org
Streptococcus pneumoniae (the pneumococcus) is a nasopharyngeal commensal and
respiratory pathogen. Most isolates express a capsule, the species-wide diversity of which …

Influenza A virus infection predisposes hosts to secondary infection with different Streptococcus pneumoniae serotypes with similar outcome but serotype-specific …

N Sharma-Chawla, V Sender, O Kershaw… - Infection and …, 2016 - Am Soc Microbiol
Influenza A virus (IAV) and Streptococcus pneumoniae are major causes of respiratory tract
infections, particularly during coinfection. The synergism between these two pathogens is …