Tissue clearing and light-sheet microscopy have a 100-year-plus history, yet these fields
have been combined only recently to facilitate novel experiments and measurements in …

Organisms are inherently three dimensional, thus comprehensive understanding of the
complicated biological system requires analysis of organs or even whole bodies in the …

Recent tissue-clearing approaches have become important alternatives to standard
histology approaches. However, light scattering in thick tissues and the size restrictions on …

This tutorial-review introduces the fundamentals of polarized light interaction with biological
tissues and presents some of the recent key polarization optical methods that have made …

Organism-level systems biology aims to identify, analyze, control and design cellular circuits
in organisms. Many experimental and computational approaches have been developed …

Citrus spp. are spread mainly in the Mediterranean basin and represent the largest fruit
source for human consumption. Postharvest losses, mainly due to diseases and metabolic …

Mammalian bodies have more than a billion cells per cubic centimeter, which makes whole-
body cell (WBC) profiling of an organism one of the ultimate challenges in biology and …

Stochastic and proliferative events initiated from a single cell can disrupt homeostatic
balance and lead to fatal disease processes such as cancer metastasis. To overcome …

Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing
role in medicine. Their adequate and effective implementation in diagnostics, surgery, and …

Homeostatic and pathological phenomena often affect multiple organs across the whole
organism. Tissue clearing methods, together with recent advances in microscopy, have …