The alkylation of 2-oxo-4, 6-diaryl-1, 2, 3, 4-tetrahydropyridine-3-carbonitrile 1 has been
carried out using different alkyl/arylating agents in solid–liquid phase-transfer catalysis …

Publisher Summary This chapter discusses the preparation and reaction of pyridines and
benzo derivatives. Condensation reactions are the most frequently used methods for the …

Selective functionalization at the α-methyl group of 1-substituted pyridin-2 (1H)-and 4 (1H)-
ones (2-and 4-pyridones) can be achieved by appropriate choice of base. n-Butyllithium was …

New methodology for the synthesis of several 4H-pyrido [1, 2-a] pyrimidin-4-ones has been
developed from commercially available 2-aminopyridines and β-oxo esters catalysed by …

Spongistatin 1 (Altohyrtin A) is a marine natural product, which was isolated in 1993 from a
species of Spongia in the Eastern Indian Ocean by Pettit and co-workers, and also from …

The use of tri-n-butyltin hydride and an initiator to mediate free radical cyclisation as a
synthetic organic process is well documented throughout the chemical literature. By using …