Plant viruses as adjuvants for next-generation vaccines and immunotherapy

N Nikitin, Y Vasiliev, A Kovalenko, E Ryabchevskaya… - Vaccines, 2023 - mdpi.com
Vaccines are the cornerstone of infectious disease control and prevention. The outbreak of
SARS-CoV-2 has confirmed the urgent need for a new approach to the design of novel …

Pluronic F127 “nanoarmor” for stabilization of Cowpea mosaic virus immunotherapy

MD Shin, E Jung, MA Moreno‐Gonzalez… - Bioengineering & …, 2024 - Wiley Online Library
Our lab demonstrated that intratumoral Cowpea mosaic virus (CPMV) is a potent antitumor
immunotherapy when used as in situ vaccine. As we pave the way for human clinical …

The Potency of Cowpea Mosaic Virus Particles for Cancer In Situ Vaccination Is Unaffected by the Specific Encapsidated Viral RNA

E Jung, YH Chung, C Mao, SN Fiering… - Molecular …, 2023 - ACS Publications
Plant virus nanoparticles can be used as drug carriers, imaging reagents, vaccine carriers,
and immune adjuvants in the formulation of intratumoral in situ cancer vaccines. One …

Cowpea mosaic virus intratumoral immunotherapy maintains stability and efficacy after long‐term storage

A Simms, Z Zhao, E Cedrone… - Bioengineering & …, 2024 - Wiley Online Library
Cowpea mosaic virus (CPMV) has demonstrated superior immune stimulation and efficacy
as an intratumoral immunotherapy, providing a strong argument for its clinical translation …

A Mannose-Modified Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Anti-Tumor Immune Response by Modulating the Tumor Microenvironment

L Wu, X Qian, W Hu, S Wang, J Yan - 2024 - preprints.org
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as a potential therapeutic strategy. The potential role of the mannose …

[图书][B] Polymer Engineering Methods to Improve the Interface Between Materials Science and Biology

Y Zheng - 2023 - search.proquest.com
Polymers are a group of materials that consist of large molecules (macromolecules)
arranged in a pattern of repeating small subunits. They can be classified into natural …

[HTML][HTML] A Plant Virus Nanoparticle Toolbox to Combat Cancer

K Hefferon, M Shahgolzari, A Yavari - pharmafocusasia.com
Plant viruses are nano-sized particles with the natural capacity to transfer and release
nucleic acids into eukaryotic cells. Plant virus-based nanoparticles (PVNPs) refer to plant …