Resilience science in psychology and related fields emerged from clinical research on risk
for psychopathology in the 1970s and matured over the ensuing decades with advances in …

The cumulative science linking stress to negative health outcomes is vast. Stress can affect
health directly, through autonomic and neuroendocrine responses, but also indirectly …

Mental health is critically important to everyone, everywhere. All over the world, mental
health needs are high but responses are insufficient and inadequate. The World mental …

Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …

Summary Background Adverse childhood experiences (ACEs) are associated with
increased health risks across the life course. We aimed to estimate the annual health and …

Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

The view that substance addiction is a brain disease, although widely accepted in the
neuroscience community, has become subject to acerbic criticism in recent years. These …

While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Suicide and self-harm are major health and societal issues worldwide, but the greatest
burden of both behaviours occurs in low-income and middle-income countries. Although …