Molecular biomarkers in multiple sclerosis

T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …

Clinical outcome measures in multiple sclerosis: a review

H Inojosa, D Schriefer, T Ziemssen - Autoimmunity reviews, 2020 - Elsevier
A proper clinical evaluation of patients with Multiple Sclerosis (MS) is of great importance to
detect MS progression. It provides important data for physicians on their daily practice as …

Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course

R Kalb, TR Brown, S Coote, K Costello… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Objectives: To provide clinicians who treat multiple sclerosis (MS) patients with evidence-
based or expert opinion–based recommendations for promoting exercise and lifestyle …

Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study

BD Trapp, M Vignos, J Dudman, A Chang… - The Lancet …, 2018 - thelancet.com
Background Demyelination of cerebral white matter is thought to drive neuronal
degeneration and permanent neurological disability in individuals with multiple sclerosis …

Patient-reported outcomes in multiple sclerosis care

E D'Amico, R Haase, T Ziemssen - Multiple sclerosis and related disorders, 2019 - Elsevier
Patient-reported outcomes (PROs) are increasingly used in multiple sclerosis (MS) research
and clinical practice for understanding the effects that the disease and its treatments have on …

Fitness, physical activity, and exercise in multiple sclerosis: a systematic review on current evidence for interactions with disease activity and progression

S Proschinger, P Kuhwand, A Rademacher… - Journal of …, 2022 - Springer
Background A moderate to high level of physical activity, including regular exercise,
represents an established behavioral and rehabilitative approach for persons with multiple …

[PDF][PDF] Multiple sclerosis: I. Symptomatology and etiology

AL Fymat - J Neurol Psychol Res, 2023 - researchnovelty.com
Multiple sclerosis (MS) is the most common autoimmune disorder of the central nervous
system. It is a chronic, debilitating, demyelinating disease caused by an autoimmune attack …

Understanding lifestyle self-management regimens that improve the life quality of people living with multiple sclerosis: a systematic review and meta-analysis

OC Wills, YC Probst - Health and quality of life outcomes, 2022 - Springer
Background Lifestyle self-management as an intervention for people living with multiple
sclerosis (plwMS) is an emerging area of research. Previous reviews have highlighted a …

Complement: Bridging the innate and adaptive immune systems in sterile inflammation

MW Lo, TM Woodruff - Journal of Leucocyte Biology, 2020 - academic.oup.com
The complement system is a collection of soluble and membrane-bound proteins that
together act as a powerful amplifier of the innate and adaptive immune systems. Although its …