The yin and yang of human soil-transmitted helminth infections
The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …
and hookworms. Soil-transmitted helminth infections rank among the most important …
The mRNA vaccine technology era and the future control of parasitic infections
Despite intensive long-term efforts, with very few exceptions, the development of effective
vaccines against parasitic infections has presented considerable challenges, given the …
vaccines against parasitic infections has presented considerable challenges, given the …
[HTML][HTML] Soil-transmitted helminths: A critical review of the impact of co-infections and implications for control and elimination
S Lebu, W Kibone, CC Muoghalu… - PLoS neglected …, 2023 - journals.plos.org
Researchers have raised the possibility that soil-transmitted helminth (STH) infections might
modify the host's immune response against other systemic infections. STH infections can …
modify the host's immune response against other systemic infections. STH infections can …
[HTML][HTML] Communication is key: Innate immune cells regulate host protection to helminths
J Peng, HG Federman, CM Hernandez… - Frontiers in …, 2022 - frontiersin.org
Parasitic helminth infections remain a significant global health issue and are responsible for
devastating morbidity and economic hardships. During infection, helminths migrate through …
devastating morbidity and economic hardships. During infection, helminths migrate through …
Why are we still a worm world in the 2020s? an overview of risk factors and endemicity for soil-transmitted helminthiasis
AFR Neto, YL Di Christine Oliveira, LM De Oliveira… - Acta parasitologica, 2023 - Springer
Purpose Soil-transmitted helminthiasis (STH) is one of the most common chronic infections
in developing countries associated with poor socioeconomic and sanitary conditions. The …
in developing countries associated with poor socioeconomic and sanitary conditions. The …
[HTML][HTML] Whipworm secretions and their roles in host-parasite interactions
RK Shears, RK Grencis - Parasites & Vectors, 2022 - Springer
Whipworm (Trichuris) is a genus of roundworms that causes gastrointestinal infections in
humans and animals. Of particular interest are T. trichiura, the causative agent of human …
humans and animals. Of particular interest are T. trichiura, the causative agent of human …
Soil-transmitted helminthic vaccines: Where are we now?
It has been tested and proven that vaccination is still the best strategy to combat infectious
diseases. However, to date, there are still no vaccines against human soil-transmitted …
diseases. However, to date, there are still no vaccines against human soil-transmitted …
[HTML][HTML] In silico design of a polypeptide as a vaccine candidate against ascariasis
FMD Evangelista, AHM van Vliet, SP Lawton… - Scientific reports, 2023 - nature.com
Ascariasis is the most prevalent zoonotic helminthic disease worldwide, and is responsible
for nutritional deficiencies, particularly hindering the physical and neurological development …
for nutritional deficiencies, particularly hindering the physical and neurological development …
[HTML][HTML] Innovative ecosystem model of vaccine lifecycle management
I Ilin, A Levina, K Frolov - Journal of Open Innovation: Technology, Market …, 2022 - mdpi.com
The COVID-19 pandemic has severely tested humanity, revealing the need to develop and
improve the medical, economic, managerial, and IT components of vaccine management …
improve the medical, economic, managerial, and IT components of vaccine management …
[HTML][HTML] Community-wide mass drug administration for soil-transmitted helminths–risk of drug resistance and mitigation strategies
N Pilotte, M Manuel, JL Walson… - Frontiers in Tropical …, 2022 - frontiersin.org
Mass drug administration programs for the control of soil-transmitted helminths (STH) in
humans most commonly utilize a single class of drugs; the benzimidazoles. Most such …
humans most commonly utilize a single class of drugs; the benzimidazoles. Most such …