[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

Human aquaporins: functional diversity and potential roles in infectious and non-infectious diseases

AK Azad, T Raihan, J Ahmed, A Hakim, TH Emon… - Frontiers in …, 2021 - frontiersin.org
Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

Evolution and functional diversity of aquaporins

RN Finn, J Cerdà - The Biological Bulletin, 2015 - journals.uchicago.edu
In this review, we provide a brief synopsis of the evolution and functional diversity of the
aquaporin gene superfamily in prokaryotic and eukaryotic organisms. Based upon the latest …

Pharmacotherapy of glaucoma

D Schmidl, L Schmetterer, G Garhöfer… - Journal of Ocular …, 2015 - liebertpub.com
Glaucoma is a group of diseases involving the optic nerve and associated structures, which
is characterized by progressive visual field loss and typical changes of the optic nerve head …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Effects of diabetic retinopathy on the barrier functions of the retinal pigment epithelium

T Xia, LJ Rizzolo - Vision research, 2017 - Elsevier
Diabetic retinopathy is a debilitating microvascular complication of diabetes mellitus. A rich
literature describes the breakdown of retinal endothelial cells and the inner blood-retinal …

Ions, the movement of water and the apoptotic volume decrease

CD Bortner, JA Cidlowski - Frontiers in cell and developmental …, 2020 - frontiersin.org
The movement of water across the cell membrane is a natural biological process that occurs
during growth, cell division, and cell death. Many cells are known to regulate changes in …

Changes in retinal glial cells with age and during development of age-related macular degeneration

DV Telegina, OS Kozhevnikova, NG Kolosova - Biochemistry (Moscow), 2018 - Springer
Age is the major risk factor in the age-related macular degeneration (AMD) which is a
complex multifactor neurodegenerative disease of the retina and the main cause of …

[HTML][HTML] The role of Müller cells in diabetic macular edema

D Lai, Y Wu, C Shao, Q Qiu - Investigative Ophthalmology & …, 2023 - tvst.arvojournals.org
Diabetic macular edema (DME) is a common complication of diabetic retinopathy and is the
leading cause of vision loss in diabetic patients. Various factors, such as metabolic disorders …

The role of retinal Müller cells in diabetic retinopathy and related therapeutic advances

S Yang, S Qi, C Wang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a significant complication of diabetes. During the pathogenesis
of retinal microangiopathy and neuronopathy, activated retinal Müller cells (RMCs) undergo …