[HTML][HTML] Pathogenic factors of Pseudomonas aeruginosa–the role of biofilm in pathogenicity and as a target for phage therapy

F Al-Wrafy, E Brzozowska, S Górska… - Advances in Hygiene and …, 2017 - phmd.pl
Pseudomonas aeruginosa is an opportunistic pathogen that can cause several acute and
chronic infections in humans, and it has become an important cause of nosocomial …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

The molecular mechanism of the type IVa pilus motors

M McCallum, S Tammam, A Khan, LL Burrows… - Nature …, 2017 - nature.com
Type IVa pili are protein filaments essential for virulence in many bacterial pathogens; they
extend and retract from the surface of bacterial cells to pull the bacteria forward. The motor …

Architecture, function, and substrates of the type II secretion system

KV Korotkov, M Sandkvist - EcoSal Plus, 2019 - Am Soc Microbiol
The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …

secA, secD, secF, yajC, and yidC contribute to the adhesion regulation of Vibrio alginolyticus

L Guo, L Huang, Y Su, Y Qin, L Zhao… - Microbiologyopen, 2018 - Wiley Online Library
Vibrio alginolyticus caused great losses to aquaculture. Adhesion is an important virulence
factor of V. alginolyticus. In this study, the relationship between V. alginolyticus adhesion …

Cyclic di-GMP binding by an assembly ATPase (PilB2) and control of type IV pilin polymerization in the Gram-positive pathogen Clostridium perfringens

WA Hendrick, MW Orr, SR Murray, VT Lee… - Journal of …, 2017 - Am Soc Microbiol
ABSTRACT The Gram-positive pathogen Clostridium perfringens possesses type IV pili
(TFP), which are extracellular fibers that are polymerized from a pool of pilin monomers in …

Structural insights into the mechanism of Type IVa pilus extension and retraction ATPase motors

V Solanki, S Kapoor, KG Thakur - The FEBS journal, 2018 - Wiley Online Library
Type IVa pili are bacterial appendages involved in diverse physiological processes,
including electron transfer in Geobacter sulfurreducens. ATP hydrolysis coupled with …

Mutation analysis of the interactions between Mycobacterium tuberculosis caseinolytic protease C1 (ClpC1) and ecumicin

IP Jung, NR Ha, AR Kim, SH Kim, MY Yoon - International journal of …, 2017 - Elsevier
Ecumicin is a well-known and potent inhibitor of Mycobacterium tuberculosis. Although the
target of ecumicin is caseinolytic protease C1 (ClpC1), the exact mechanism by which …

Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease

CS Rule, YJ Park, JR Delarosa, S Turley, WGJ Hol… - Msphere, 2020 - Am Soc Microbiol
The type II secretion system (T2SS) is a conserved transport pathway responsible for the
secretion of a range of virulence factors by many pathogens, including Vibrio cholerae …

Effect of Excessive Zinc on Pseudomonas Aeruginosa and Susceptibility to Gastrointestinal Inflammation

T Wu - 2020 - search.proquest.com
Zinc supplements are commonly used to treat zinc deficiency and to reduce the clinical
symptoms in several gastrointestinal inflammatory disorders. However, the combination of …