Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …

Meiosis produces haploid gametes through a succession of chromosomal events, including
pairing, synapsis, and recombination. Mechanisms that orchestrate these events remain …

Protein modification by SUMO helps orchestrate the elaborate events of meiosis to faithfully
produce haploid gametes. To date, only a handful of meiotic SUMO targets have been …

Mitochondrial fusion and fission (mitochondrial dynamics) are homeostatic processes that
safeguard normal cellular function. This relationship is especially strong in tissues with …

Background Most mammalian genes display alternative cleavage and polyadenylation
(APA). Previous studies have indicated preferential expression of APA isoforms with short …

Background The formation of matured and individual sperm involves a series of molecular
and spectacular morphological changes of the developing cysts in Drosophila melanogaster …

STUDY QUESTION Do spermatogonia, including spermatogonial stem cells (SSCs),
undergo metabolic changes during prepubertal development? SUMMARY ANSWER Here …

High-throughput transcriptomics and proteomics approaches have recently identified a large
number of germ cell–specific genes with many that remain to be studied through functional …

During meiosis, the formation of crossovers (CO s) generates genetic variation and provides
physical links that are essential for accurate chromosome segregation. CO s occur in the …