Comprehensive review on various strategies for antimalarial drug discovery
M Mishra, VK Mishra, V Kashaw, AK Iyer… - European journal of …, 2017 - Elsevier
The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …
limiting our ability to manage this severe disease and finally lead to a massive global health …
Malaria: an update on current chemotherapy
BJ Visser, M van Vugt, MP Grobusch - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …
First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of observational studies
S Dellicour, E Sevene, R McGready, H Tinto… - PLoS …, 2017 - journals.plos.org
Background Animal embryotoxicity data, and the scarcity of safety data in human
pregnancies, have prevented artemisinin derivatives from being recommended for malaria …
pregnancies, have prevented artemisinin derivatives from being recommended for malaria …
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines
KAJ Al Khaja, RP Sequeira - Malaria journal, 2021 - Springer
Abstract Background Malaria caused by Plasmodium falciparum in pregnancy can result in
adverse maternal and fetal sequelae. This review evaluated the adherence of the national …
adverse maternal and fetal sequelae. This review evaluated the adherence of the national …
New approaches in antimalarial drug discovery and development: a review
ACC Aguiar, EMM da Rocha, NB de Souza… - Memorias do Instituto …, 2012 - SciELO Brasil
Malaria remains a major world health problem following the emergence and spread of
Plasmodium falciparum that is resistant to the majority of antimalarial drugs. This problem …
Plasmodium falciparum that is resistant to the majority of antimalarial drugs. This problem …
Antimalarial chemotherapy: natural product inspired development of preclinical and clinical candidates with diverse mechanisms of action: miniperspective
E Fernandez-Alvaro, WD Hong, GL Nixon… - Journal of medicinal …, 2016 - ACS Publications
Natural products have played a pivotal role in malaria chemotherapy progressing from
quinine and artemisinin to ozonide-based compounds. Many of these natural products have …
quinine and artemisinin to ozonide-based compounds. Many of these natural products have …
Addressing barriers to the development and adoption of rapid diagnostic tests in global health
Sažetak Immunochromatographic rapid diagnostic tests (RDTs) have demonstrated
significant potential for use as point-of-care diagnostic tests in resource-limited settings …
significant potential for use as point-of-care diagnostic tests in resource-limited settings …
Practical gram-scale synthesis of iboxamycin, a potent antibiotic candidate
JD Mason, DW Terwilliger, AR Pote… - Journal of the American …, 2021 - ACS Publications
A gram-scale synthesis of iboxamycin, an antibiotic candidate bearing a fused bicyclic
amino acid residue, is presented. A pivotal transformation in the route involves an …
amino acid residue, is presented. A pivotal transformation in the route involves an …
Malaria therapeutics: are we close enough?
Malaria is a vector-borne parasitic disease caused by the apicomplexan protozoan parasite
Plasmodium. Malaria is a significant health problem and the leading cause of …
Plasmodium. Malaria is a significant health problem and the leading cause of …
An insight into the recent development of the clinical candidates for the treatment of malaria and their target proteins
Malaria is an endemic disease, prevalent in tropical and subtropical regions which cost half
of million deaths annually. The eradication of malaria is one of the global health priority …
of million deaths annually. The eradication of malaria is one of the global health priority …