Brain death and care of the organ donor

L Kumar - Journal of Anaesthesiology Clinical Pharmacology, 2016 - journals.lww.com
Brain death has specific implications for organ donation with the potential for saving several
lives. Awareness on maintenance of the brain dead has increased over the last decade with …

[HTML][HTML] Medical management of brain-dead organ donors

ASMT Anwar, J Lee - Acute and Critical Care, 2019 - ncbi.nlm.nih.gov
With improving healthcare services, the demand for organ transplants has been increasing
daily worldwide. Deceased organ donors serve as a good alternative option to meet this …

Donor heart selection: Evidence-based guidelines for providers

H Copeland, I Knezevic, DA Baran, V Rao… - The Journal of Heart and …, 2023 - Elsevier
The proposed donor heart selection guidelines provide evidence-based and expert-
consensus recommendations for the selection of donor hearts following brain death. These …

ICU management of the potential organ donor: state of the art

CB Maciel, DM Greer - Current neurology and neuroscience reports, 2016 - Springer
End-organ failure is associated with high mortality and morbidity, in addition to increased
health care costs. Organ transplantation is the only definitive treatment that can improve …

Ischemia/reperfusion-associated tubular cells injury in renal transplantation: Can metabolomics inform about mechanisms and help identify new therapeutic targets?

C Barin-Le Guellec, B Largeau, D Bon… - Pharmacological …, 2018 - Elsevier
Tubular cells are central targets of ischemia-reperfusion (I/R) injury in kidney transplantation.
Inflammation and metabolic disturbances occurring within these cells are deleterious by …

Physiologic features of brain death

EO Essien, K Fioretti, TM Scalea… - The American …, 2017 - journals.sagepub.com
Brain death is known to be associated with physiologic derangements but their incidence is
poorly described. Knowledge of the changes that occur during brain death is important for …

Increased procurement of thoracic donor organs after thyroid hormone therapy

D Novitzky, Z Mi, JF Collins, DKC Cooper - Seminars in Thoracic and …, 2015 - Elsevier
Hormonal therapy to the brain-dead organ donor can include thyroid hormone
(triiodothyronine [T 3] or levothyroxine [T 4]), antidiuretic hormone, corticosteroids, or insulin …

Pharmacists' guide to the management of organ donors after brain death

C Korte, JL Garber, JL Descourouez… - American Journal of …, 2016 - academic.oup.com
Purpose This article reviews organ donor pathophysiology as it relates to medication use
with the goal of maximizing the successful procurement and transplantation of donor organs …

Anti-apoptotic effects of 3, 3', 5-triiodo-L-thyronine in the liver of brain-dead rats

RA Rebolledo, AC Van Erp, PJ Ottens… - PLoS …, 2015 - journals.plos.org
Background Thyroid hormone treatment in brain-dead organ donors has been extensively
studied and applied in the clinical setting. However, its clinical applicability remains …

Organ donation protocols

CB Maciel, DY Hwang, DM Greer - Handbook of clinical neurology, 2017 - Elsevier
Organ transplantation improves survival and quality of life in patients with end-organ failure.
Waiting lists continue to grow across the world despite remarkable advances in the …