Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease in which immune
disorders lead to autoreactive immune responses and cause inflammation and tissue …

Autoimmune inflammation is caused by the loss of tolerance to specific self-antigens and
can result in organ-specific or systemic disorders. Systemic autoimmune diseases affect a …

Importance Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by inflammation and immune-mediated injury to multiple organ systems …

The analysis of cerebrospinal fluid (CSF) remains a valuable diagnostic tool in the
evaluation of inflammatory and infectious conditions involving the brain, spinal cord, and …

Lupus nephritis is an important manifestation of systemic lupus erythematosus, which leads
to chronic kidney disease, kidney failure, and can result in mortality. About 35%–60% of …

Background Lupus nephritis (LN) manifests systemic lupus erythematosus (SLE) and is
characterized by various clinical and laboratory features. This study aimed to …

The development of new medicines for systemic lupus erythematosus (SLE) has not
addressed unmet clinical need, with only three drugs receiving regulatory approval for SLE …

Background Validation of protective associations of the lupus low disease activity state
(LLDAS) against flare, irreversible damage, health-related quality of life, and mortality has …

Type I interferons (IFN-I) are key immune messenger molecules that play an important role
in viral defense. They act as a bridge between microbe sensing, immune function …

Objective This international task force aimed to provide healthcare professionals and
persons living with systemic lupus erythematosus (SLE) with consensus-based …