[HTML][HTML] Cognitive function in older adults with cancer: assessment, management, and research opportunities

A Magnuson, T Ahles, BT Chen… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Cancer is primarily a disease of aging, and the majority of new diagnoses of cancer occur in
patients $65 years of age (herein referred to as older). 1 At the same time, cancer and its …

Applying a life course biological age framework to improving the care of individuals with adult cancers: review and research recommendations

JS Mandelblatt, TA Ahles, ME Lippman, C Isaacs… - JAMA …, 2021 - jamanetwork.com
Importance The practice of oncology will increasingly involve the care of a growing
population of individuals with midlife and late-life cancers. Managing cancer in these …

Loneliness and mental health during the COVID‐19 pandemic in older breast cancer survivors and noncancer controls

KE Rentscher, X Zhou, BJ Small, HJ Cohen… - Cancer, 2021 - Wiley Online Library
Background The coronavirus disease 2019 (COVID‐19) pandemic has had wide‐ranging
health effects and increased isolation. Older with cancer patients might be especially …

Elevated C-reactive protein and subsequent patient-reported cognitive problems in older breast cancer survivors: the thinking and living with cancer study

JE Carroll, ZM Nakamura, BJ Small, X Zhou… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To examine longitudinal relationships between levels of C-reactive protein
(CRP) and cognition in older breast cancer survivors and noncancer controls. METHODS …

[HTML][HTML] Trajectories, transitions, and trends in frailty among older adults: a review

EO Hoogendijk, E Dent - Annals of geriatric medicine and research, 2022 - ncbi.nlm.nih.gov
Frailty is an age-related clinical state associated with deterioration across multiple
physiological systems and a leading cause of morbidity and mortality later in life. To …

Inflammation and clinical decline after adjuvant chemotherapy in older adults with breast cancer: results from the Hurria Older Patients Prospective Study

J Ji, CL Sun, HJ Cohen, T Synold, H Muss… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Older breast cancer survivors are at increased risk of clinical decline after
adjuvant chemotherapy. This study aimed to evaluate whether inflammatory markers …

Premature aging as an accumulation of deficits in young adult survivors of pediatric cancer

ALM Williams, J Mandelblatt, M Wang… - JNCI: Journal of the …, 2023 - academic.oup.com
Background We aimed to characterize premature aging as an accumulation of deficits in
survivors of pediatric cancer compared with community controls and examine associations …

Physiologic frailty and neurocognitive decline among young-adult childhood cancer survivors: a prospective study from the St Jude Lifetime Cohort

ALM Williams, KR Krull, CR Howell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Eight percent of young-adult childhood cancer survivors meet criteria for frailty,
an aging phenotype associated with poor health. In the elderly general population, frailty is …

The prevalence of frailty among breast cancer patients: a systematic review and meta-analysis

S Wang, T Yang, W Qiang, A Shen, Z Zhao… - Supportive Care in …, 2022 - Springer
Purpose Coexistence of frailty and breast cancer (BC) is related to a higher risk of
hospitalization, mortality, and falls. Given the potential reversibility of frailty, investigating its …

The aging–cancer cycle: mechanisms and opportunities for intervention

MS Sedrak, HJ Cohen - The Journals of Gerontology: Series A, 2023 - academic.oup.com
Aging is the largest risk factor for the development of cancer. A growing body of literature
indicates that aging and cancer often play a somewhat reciprocal relationship at various …