Oral nanomedicine: challenges and opportunities
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …
infection, and complications and has a higher compliance rate for patients with diverse …
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …
compliance of the patient. Oral nanomedicines have been developed to overcome the …
Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update
S Liu, X Wen, X Zhang, S Mao - Expert opinion on drug delivery, 2023 - Taylor & Francis
Introduction Biomacromolecules have proven to be an attractive choice for treating diseases
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
The spatiotemporal journey of nanomedicines in solid tumors on their therapeutic efficacy
The rapid development of nanomedicines is revolutionizing the landscape of cancer
treatment, while effectively delivering them into solid tumors remains a formidable challenge …
treatment, while effectively delivering them into solid tumors remains a formidable challenge …
Selective organ targeting nanoparticles: from design to clinical translation
J Li, H Wang - Nanoscale Horizons, 2023 - pubs.rsc.org
Targeting nanoparticle is a very promising therapeutic approach that can precisely target
specific sites to treat diseases. Research on nanoscale drug delivery systems has made …
specific sites to treat diseases. Research on nanoscale drug delivery systems has made …
[HTML][HTML] Chitosan-based nano-smart drug delivery system in breast cancer therapy
Despite recent advances, cancer remains the primary killer on a global scale. Numerous
forms of research have been conducted to discover novel and efficient anticancer …
forms of research have been conducted to discover novel and efficient anticancer …
[HTML][HTML] N-Sulfonyl amidine polypeptides: new polymeric biomaterials with conformation transition responsive to tumor acidity
X Xu, J Ma, A Wang, N Zheng - Chemical Science, 2024 - pubs.rsc.org
Manipulation of pH responsiveness is a frequently employed tactic in the formulation of
trigger-responsive nanomaterials. It offers an avenue for “smart” designs capitalizing on …
trigger-responsive nanomaterials. It offers an avenue for “smart” designs capitalizing on …
Inhaled immunoantimicrobials for the treatment of chronic obstructive pulmonary disease
J Zhu, X Li, Y Zhou, C Ge, X Li, M Hou, Y Wei… - Science …, 2024 - science.org
Effective therapeutic modalities and drug administration strategies for the treatment of
chronic obstructive pulmonary disease (COPD) exacerbations are lacking. Here, mucus and …
chronic obstructive pulmonary disease (COPD) exacerbations are lacking. Here, mucus and …
Oral delivery of berberine by liver-targeted zwitterionic nanoparticles to overcome multi-intestinal barriers and extend insulin treatment duration
Y Ma, C Li, F Han, Y Liu, UE Hani, Y Zhong… - Chemical Engineering …, 2024 - Elsevier
Oral insulin is a promising strategy due to its favorable patient compliance and repeatable
administration, while it faces with critical problem of multi-intestinal barriers. Moreover, the …
administration, while it faces with critical problem of multi-intestinal barriers. Moreover, the …
Helical‐Like Assembly of Nateglinide as Coating for Oral Delivery of Insulin and Their Synergistic Prevention of Diabetes Mellitus
Y Li, L Chen, Y Xu, S Li, H Yan, T Chen… - Advanced …, 2023 - Wiley Online Library
Oral delivery of antidiabetic active components promises to free millions of people from daily
suffering who require routine injections. However, oral insulin (Ins) and other short‐acting …
suffering who require routine injections. However, oral insulin (Ins) and other short‐acting …