[HTML][HTML] Pathophysiology of acute kidney injury
DP Basile, MD Anderson, TA Sutton - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …
[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An …
compartment as exosomes or shed from the surface membranes of most cell types. An …
Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair
AM Hocking, NS Gibran - Experimental cell research, 2010 - Elsevier
Cutaneous wounds persist as a health care crisis in spite of increased understanding of the
cellular and molecular responses to injury. Contributing significantly to this crisis is the lack …
cellular and molecular responses to injury. Contributing significantly to this crisis is the lack …
Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements
J Doorn, G Moll, K Le Blanc… - … Engineering Part B …, 2012 - liebertpub.com
Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …
signals that are transmitted over short distances between different cell types. In the human …
Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
YT Chen, CK Sun, YC Lin, LT Chang, YL Chen… - Journal of translational …, 2011 - Springer
Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …
Additional benefit of combined therapy with melatonin and apoptotic adipose‐derived mesenchymal stem cell against sepsis‐induced kidney injury
HH Chen, KC Lin, CG Wallace, YT Chen… - Journal of pineal …, 2014 - Wiley Online Library
This study tested whether combined therapy with melatonin and apoptotic adipose‐derived
mesenchymal stem cells (A‐ADMSC s) offered additional benefit in ameliorating sepsis …
mesenchymal stem cells (A‐ADMSC s) offered additional benefit in ameliorating sepsis …
Organ repair and regeneration: an overview
JA Baddour, K Sousounis… - Birth Defects Research …, 2012 - Wiley Online Library
A number of organs have the intrinsic ability to regenerate, a distinctive feature that varies
among organisms. Organ regeneration is a process not fully yet understood. However, when …
among organisms. Organ regeneration is a process not fully yet understood. However, when …
Paracrine/endocrine mechanism of stem cells on kidney repair: role of microvesicle-mediated transfer of genetic information
Transfer of genetic information from injured cells may explain stem cell functional and
phenotypic changes without the need for transdifferentiation into tissue cells. On the …
phenotypic changes without the need for transdifferentiation into tissue cells. On the …
Adipose‐derived mesenchymal cells for bone regereneration: State of the art
M Barba, C Cicione, C Bernardini… - BioMed research …, 2013 - Wiley Online Library
Adipose tissue represents a hot topic in regenerative medicine because of the tissue source
abundance, the relatively easy retrieval, and the inherent biological properties of …
abundance, the relatively easy retrieval, and the inherent biological properties of …
Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury
VR Burst, M Gillis, F Pütsch, R Herzog… - Nephron Experimental …, 2010 - karger.com
Background: Although renal tubular epithelium has a great capacity for repair it has been
suggested that the administration of mesenchymal stem cells may accelerate the recovery …
suggested that the administration of mesenchymal stem cells may accelerate the recovery …