Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanism

R Regev, D Yeheskely-Hayon, H Katzir… - Biochemical …, 2005 - Elsevier
The objectives of the present work are to characterize the transport of mitoxantrone and
three anthracyclines in terms of binding to the membrane surface, flip-flop across the lipid …

[HTML][HTML] Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles.

FA Sinicrope, PK Dudeja, BM Bissonnette… - Journal of Biological …, 1992 - Elsevier
P-glycoprotein (P-gp) is believed to function as an ATP-dependent efflux pump for natural
product anti-cancer drugs in multidrug-resistant (MDR) tumor cells and in certain normal …

Chemical and Biophysical Changes in the Plasma Membrane during Cold Acclimation of Mulberry Bark Cells (Morus bombycis Koidz. cv Goroji)

S Yoshida - Plant Physiology, 1984 - academic.oup.com
The lipid and protein composition of the plasma membrane isolated from mulberry (Morus
bombycis Koidz.) bark cells was analyzed throughout the cold acclimation period under …

Lipid Rafts in Cryptococcus neoformans Concentrate the Virulence Determinants Phospholipase B1 and Cu/Zn Superoxide Dismutase

AR Siafakas, LC Wright, TC Sorrell, JT Djordjevic - Eukaryotic cell, 2006 - Am Soc Microbiol
Lipid rafts have been identified in the membranes of mammalian cells, the yeast
Saccharomyces cerevisiae, and the pathogenic fungus Candida albicans. Formed by a …

Interactions of flavan-3-ols and procyanidins with membranes: mechanisms and the physiological relevance

SV Verstraeten, CG Fraga, PI Oteiza - Food & function, 2015 - pubs.rsc.org
Flavonoids are a type of phenolic compound widely present in edible plants. A great number
of health benefits have been ascribed to flavonoid consumption in the human population …

Fatty acid uptake by Caco-2 human intestinal cells

PJ Trotter, SY Ho, J Storch - Journal of lipid research, 1996 - Elsevier
The Caco-2 human enterocytic cell line was used to study the kinetics and mechanism of
intestinal long chain fatty acid uptake. Initial rates of palmitate (16: 0), oleate (18: 1), and …

[图书][B] Target organ toxicity in marine and freshwater teleosts: Systems

D Schlenk, WH Benson - 2001 - taylorfrancis.com
Addressing the numerous gaps in current information, Target Organ Toxicology in Marine
and Freshwater Teleosts is an essential resource for researchers and professionals in …

Common mechanisms of monoacylglycerol and fatty acid uptake by human intestinal Caco-2 cells

SY Ho, J Storch - American Journal of Physiology-Cell …, 2001 - journals.physiology.org
Free fatty acids (FFA) and sn-2-monoacylglycerol (sn-2-MG), the two hydrolysis products of
dietary triacylglycerol, are absorbed from the lumen into polarized enterocytes that line the …

Oligomerization of Vibrio cholerae cytolysin yields a pentameric pore and has a dual specificity for cholesterol and sphingolipids in the target membrane

A Zitzer, O Zitzer, S Bhakdi, M Palmer - Journal of Biological Chemistry, 1999 - ASBMB
Vibrio cholerae cytolysin permeabilizes animal cell membranes. Upon binding to the target
lipid bilayer, the protein assembles into homo-oligomeric pores of an as yet unknown …

Variations in dietary triacylglycerol saturation alter the lipid composition and fluidity of rat intestinal plasma membranes

TA Brasitus, NO Davidson, D Schachter - Biochimica et Biophysica Acta …, 1985 - Elsevier
Rats were maintained on nutritionally complete diets enriched in unsaturated (corn oil) or
saturated (butter fat) triacylglycerols. After 6 weeks, significant differences in the lipid …