The beneficial effects of adipose-derived stem cell conditioned medium (ADSC-CM) on skin
regeneration have been reported. Although the mechanism of how ADSC-CM promotes skin …

Candida auris is an enigmatic yeast that provides substantial global risk in health care
facilities and intensive care units. A unique phenotype exhibited by certain isolates of C …

Tight junction (TJ) proteins are known to be involved in proliferation and differentiation.
These processes are essential for normal skin wound healing. Here, we investigated the TJ …

Connexin43 (Cx43) has roles in cell–cell communication as well as channel independent
roles in regulating motility and migration. Loss of function approaches to decrease Cx43 …

Connexins form gap junctions that function as intercellular channels and hemichannels that
form a conduit between the cytoplasm and extracellular fluid when open. Peptide inhibitors …

The heart is a complex organ composed of multiple cell types, including cardiomyocytes and
different non-myocyte populations, all working closely together to determine the hearts …

Recent studies have shown that Connexin43 mimetic peptide (Cx43 MP) can prevent
secondary damage following several retinal ischemic and inflammatory disorders by …

Gap junctions (GJ) and connexins play integral roles in cellular physiology and have been
found to be involved in multiple pathophysiological states from cancer to cardiovascular …

Skin lesions are common events and we have evolved to rapidly heal them in order to
maintain homeostasis and prevent infection and sepsis. Most acute wounds heal without …

Melanoma cells interact with and depend on seemingly normal cells in their tumour
microenvironment to allow the acquisition of the hallmarks of solid cancer. In general, there …