It is well established that stress has a major impact on memory, driven by the concerted
action of various stress mediators on the brain. Recent years, however, have seen …

Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …

BACKGROUND Myelin, produced by oligodendrocytes, supports the rapid and
synchronized transfer of information across the central nervous system (CNS). Earlier views …

The amygdala has long been associated with emotion and motivation, playing an essential
part in processing both fearful and rewarding environmental stimuli. How can a single …

Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …

Sophisticated behavioral paradigms partnered with the emergence of increasingly selective
techniques to target the basolateral amygdala (BLA) have resulted in an enhanced …

This report calls on the nation—its leaders, its mental health research and service provision
agencies, its schools, its primary care medical systems, its community-based organizations …

The synapse is the functional unit of the brain. During the last several decades we have
acquired a great deal of information on its structure, molecular components, and …