From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models
Despite the tremendous advances in cancer treatment, resistance to chemotherapeutic
agents impedes higher success rates and accounts for major relapses in cancer therapy …
agents impedes higher success rates and accounts for major relapses in cancer therapy …
The effect of ABCB1 polymorphisms on the outcome of breast cancer treatment
S Tulsyan, RD Mittal, B Mittal - … and personalized medicine, 2016 - Taylor & Francis
The ABCB1 gene encodes a permeability glycoprotein, which is one of the most extensively
studied human adenosine-triphosphate (ATP)-dependent efflux transporters. Permeability …
studied human adenosine-triphosphate (ATP)-dependent efflux transporters. Permeability …
[HTML][HTML] Effect of ABC transporter expression and mutational status on survival rates of cancer patients
O Kadioglu, MEM Saeed, M Munder, A Spuller… - Biomedicine & …, 2020 - Elsevier
ATP-binding cassette (ABC) transporters mediate multidrug resistance in cancer. In contrast
to DNA single nucleotide polymorphisms in normal tissues, the role of mutations in tumors is …
to DNA single nucleotide polymorphisms in normal tissues, the role of mutations in tumors is …
Ethnogeographic and inter-individual variability of human ABC transporters
ATP-binding cassette (ABC) transporters constitute a superfamily of 48 structurally similar
membrane transporters that mediate the ATP-dependent cellular export of a plethora of …
membrane transporters that mediate the ATP-dependent cellular export of a plethora of …
The role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells
Y Zhang, XD Mu, EZ Li, Y Luo, N Song, XJ Qu… - International journal of …, 2013 - mdpi.com
Recent studies indicate that β-elemene, a compound isolated from the Chinese herbal
medicine Curcuma wenyujin, is capable of reversing tumor MDR, although the mechanism …
medicine Curcuma wenyujin, is capable of reversing tumor MDR, although the mechanism …
Genetic influences in breast cancer drug resistance
A Daniyal, I Santoso, NHP Gunawan… - Breast cancer: targets …, 2021 - Taylor & Francis
Breast cancer is the most common cancer in adult women aged 20 to 50 years. The
therapeutic regimens that are commonly recommended to treat breast cancer are human …
therapeutic regimens that are commonly recommended to treat breast cancer are human …
[PDF][PDF] 1236 C/T and 3435 C/T polymorphisms of the ABCB1 gene in Mexican breast cancer patients
SA Gutierrez-Rubio, A Quintero-Ramos… - Genet Mol …, 2015 - researchgate.net
1236 C/T and 3435 C/T polymorphisms of the ABCB1 gene in Mexican breast cancer patients
Page 1 ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (1): 1250-1259 …
Page 1 ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (1): 1250-1259 …
Genetic variants of ABC and SLC transporter genes and chronic myeloid leukaemia: impact on susceptibility and prognosis
R Alves, AC Gonçalves, J Jorge, G Marques… - International Journal of …, 2022 - mdpi.com
Solute carrier (SLC) and ATP-binding cassette (ABC) transporters comprise a variety of
proteins expressed on cell membranes responsible for intrusion or extrusion of substrates …
proteins expressed on cell membranes responsible for intrusion or extrusion of substrates …
ABCB1 haplotypes are associated with P‑gp activity and affect a major molecular response in chronic myeloid leukemia patients treated with a standard dose of …
D Vivona, LT Lima, AC Rodrigues… - Oncology …, 2014 - spandidos-publications.com
Despite the high efficacy of imatinib mesylate (IM) treatment for chronic myeloid leukemia
(CML) patients, some individuals develop resistance due to impaired bioavailability. It has …
(CML) patients, some individuals develop resistance due to impaired bioavailability. It has …
The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case–control studies
LH Wang, YB Song, WL Zheng, L Jiang, WL Ma - Cancer cell international, 2013 - Springer
Background The multidrug resistance (MDR) 1 gene encodes a 170-kDa membrane
transporter called P-glycoprotein, which plays an important role in protecting cells against …
transporter called P-glycoprotein, which plays an important role in protecting cells against …