Mitochondria in health, disease, and aging
JS Harrington, SW Ryter, M Plataki… - Physiological …, 2023 - journals.physiology.org
Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
Reinforcement learning in healthcare: A survey
As a subfield of machine learning, reinforcement learning (RL) aims at optimizing decision
making by using interaction samples of an agent with its environment and the potentially …
making by using interaction samples of an agent with its environment and the potentially …
Plants as sources of anti-inflammatory agents
CR Nunes, M Barreto Arantes… - Molecules, 2020 - mdpi.com
Plants represent the main source of molecules for the development of new drugs, which
intensifies the interest of transnational industries in searching for substances obtained from …
intensifies the interest of transnational industries in searching for substances obtained from …
The artificial intelligence clinician learns optimal treatment strategies for sepsis in intensive care
Sepsis is the third leading cause of death worldwide and the main cause of mortality in
hospitals,–, but the best treatment strategy remains uncertain. In particular, evidence …
hospitals,–, but the best treatment strategy remains uncertain. In particular, evidence …
Sepsis associated acute kidney injury
JT Poston, JL Koyner - Bmj, 2019 - bmj.com
Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …
infection. One of the most common organs affected is the kidneys, resulting in sepsis …
What are the respiratory effects of e-cigarettes?
Electronic cigarettes (e-cigarettes) are alternative, non-combustible tobacco products that
generate an inhalable aerosol containing nicotine, flavors, propylene glycol, and vegetable …
generate an inhalable aerosol containing nicotine, flavors, propylene glycol, and vegetable …
Living leukocyte‐based drug delivery systems
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
Intrinsic radical species scavenging activities of tea polyphenols nanoparticles block pyroptosis in endotoxin-induced sepsis
Y Chen, R Luo, J Li, S Wang, J Ding, K Zhao, B Lu… - Acs Nano, 2022 - ACS Publications
Sepsis, a life-threating illness caused by deregulated host immune responses to infections,
is characterized by overproduction of multiple reactive oxygen and nitrogen species (RONS) …
is characterized by overproduction of multiple reactive oxygen and nitrogen species (RONS) …
Innate immune receptors in platelets and platelet-leukocyte interactions
PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …
inflammatory effector cells that can influence both innate and adaptive immune responses …
Emerging pyroptosis-engineered nanobiotechnologies regulate cancers and inflammatory diseases: A double-edged sword
Y Zhang, C Fang, W Zhang, K Zhang - Matter, 2022 - cell.com
Pyroptosis is closely associated with tumors and inflammatory diseases. By enhancing
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …