Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases

Y Huang, L Yang - Stem cell research & therapy, 2021 - Springer
Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Mesenchymal stem cell-derived extracellular vesicles in therapy against fibrotic diseases

Y Huang, L Yang - Stem Cell Research & Therapy, 2021 - Springer
Fibrosis is likely to occur in many tissues and organs to induce cicatrisation and dysfunction.
The therapeutic regimens for delaying and even reversing fibrosis are quite limited at …

Novel drug delivery strategies for antidepressant active ingredients from natural medicinal plants: the state of the art

S Yuan, T Ma, YN Zhang, N Wang, Z Baloch… - Journal of …, 2023 - Springer
Depression is a severe mental disorder among public health issues. Researchers in the field
of mental health and clinical psychiatrists have long been faced with difficulties in slow …

Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury

L Li, Y Shen, Z Tang, Y Yang, Z Fu, D Ni, X Cai - Exploration, 2023 - Wiley Online Library
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal
function, and is associated with a high risk of death. Many pathological changes happen in …

Non-Classical Intercellular Communications: Basic Mechanisms and Roles in Biology and Medicine

N Polyakova, M Kalashnikova, A Belyavsky - International Journal of …, 2023 - mdpi.com
In multicellular organisms, interactions between cells and intercellular communications form
the very basis of the organism's survival, the functioning of its systems, the maintenance of …

Molecular mechanisms of mesenchymal stem cell-based therapy in acute kidney injury

PW Lee, BS Wu, CY Yang, OKS Lee - International journal of molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) causes a lot of harm to human health but is treated by only
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …

细胞外囊泡治疗急性肾损伤临床前研究的Meta 分析

李清茹, 王一帆, 陈冠廷, 石若玉, 张琳琪 - 中国组织工程研究, 2023 - cjter.com
细胞外囊泡治疗急性肾损伤临床前研究的Meta分析 中国组织工程研究 首页 关于本刊 编委会
在线投稿 期刊公告 出版道德 OA政策 作者学院 在线问答 联系我们 English 中国组织工程研究 ›› …

[HTML][HTML] 米托蒽醌甲磺酸盐预处理脂肪间充质干细胞对犬糖尿病的治疗效果评价

谭宁, 李巴仑, 韩苗, 李琛琛, 景远翔, 寇正, 李娜… - 畜牧兽医学报, 2024 - html.rhhz.net
本研究在高脂饮食(high-fat diet, HFD) 饲喂和链脲佐菌素(streptozotin, STZ)
注射的联合作用下成功建立小鼠及犬糖尿病模型, 旨在探究米托蒽醌甲磺酸盐(mitoquionl …

[HTML][HTML] Emerging role of extracellular vesicles in kidney diseases

H Xiang, C Zhang, J Xiong - Frontiers in Pharmacology, 2022 - frontiersin.org
Many types of renal disease eventually progress to end-stage renal disease, which can only
be maintained by renal replacement therapy. Therefore, kidney diseases now contribute …

Spermidine Retarded the Senescence of Multipotent Mesenchymal Stromal Cells In Vitro and In Vivo through SIRT3‐Mediated Antioxidation

H Huang, W Zhang, J Su, B Zhou… - Stem Cells …, 2023 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) expand in vitro and undergo replicative
senescence, thereby restricting their clinical utilization. Thus, an effective strategy is required …