Anticancer potential of bioactive molecule luteolin and its analogs: an update

NJ Basha, SM Basavarajaiah - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
Literature evidence that natural products are potential bioactive components for lead
compounds in drug discovery. These molecules have distinctive chemical structures that …

Cancer protective role of selected dietary polyphenols via modulating Keap1/Nrf2/ARE and interconnected signaling pathways

MA Islam, MM Medha, AU Nahar, MA Al Fahad… - Nutrition and …, 2023 - Taylor & Francis
The Kelch-like ECH associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2
(Nrf2)/antioxidant response elements (ARE) signaling pathway is considered a master …

[HTML][HTML] Signaling pathways and natural compounds in triple-negative breast cancer cell line

C Dewi, A Fristiohady, R Amalia, NK Khairul Ikram… - Molecules, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer,
having a poor prognosis and rapid metastases. TNBC is characterized by the absence of …

[HTML][HTML] Salvia miltiorrhiza in cancer: Potential role in regulating MicroRNAs and epigenetic enzymes

M Lu, X Lan, X Wu, X Fang, Y Zhang, H Luo… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs are small non-coding RNAs that play important roles in gene regulation by
influencing the translation and longevity of various target mRNAs and the expression of …

Phytometabolites as modulators of breast cancer: a comprehensive review of mechanistic insights

P Sharma, K Gupta, SK Khandai, S Malik, S Thareja - Medical Oncology, 2024 - Springer
Breast cancer (BC) is a highly debilitating malignancy affecting females globally and
imposing a substantial burden on healthcare systems in both developed and developing …

[HTML][HTML] Drosophila model and network pharmacology to explore novel targets and novel active components of Chinese traditional medications for treating kidney …

S Zhang, J Zhu, Y Ju, M Lv, R Yang, Y Li, Y Miao… - Pharmacological …, 2023 - Elsevier
Background Kidney stone disease is a common urological and metabolic disease in the
world. Many traditional Chinese medications (TCMs) are considered to be effective in …

[HTML][HTML] Breviscapine regulates the proliferation, migration, invasion, and apoptosis of colorectal cancer cells via the PI3K/AKT pathway

P Niu, F Liu, F Lei, J Peng, Y Wang, J Zhao, Z Gao… - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is ranked as one of the most common malignancies with a high
death rate. It has been discovered that breviscapine can alter the progression and …

Huangqi Sijunzi decoction for treating cancer-related fatigue in breast cancer patients: a randomized trial and network pharmacology study

Y Cui, J Mi, Y Feng, L Li, Y Wang, J Hu… - Nan Fang yi ke da xue …, 2022 - europepmc.org
Objective To evaluate the clinical efficacy of Huangqi Sijunzi decoction (HQSJZD) for
treating cancer-related fatigue (CRF) of spleen and stomach Qi deficiency type after …

[HTML][HTML] Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells

A Mazurakova, L Koklesova, D Vybohova… - Frontiers in …, 2023 - frontiersin.org
Significant limitations of the reactive medical approach in breast cancer management are
clearly reflected by alarming statistics recorded worldwide. According to the WHO updates …

[HTML][HTML] Luteolin: A flavonoid with a multifaceted anticancer potential

P Prasher, M Sharma, SK Singh, M Gulati… - Cancer Cell …, 2022 - Springer
Therapeutic effect of phytochemicals has been emphasized in the traditional medicine
owing to the presence of bioactive molecules, such as polyphenols. Luteolin is a flavone …