Amorphous solid dispersions (ASDs) are among the most popular and widely studied
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …

Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

The primary focus of the research is to study the role of cocrystal and amorphous solid
dispersion approaches for enhancing solubility and preserving the stability of a poorly …

Co-processing of APIs, the practice of creating multi-component APIs directly in chemical
processing facilities used to make drug substance, is gaining increased attention with a view …

Cancer treatment has improved over the past decades, but a major challenge lies in drug
formulation, specifically for oral administration. Most anticancer drugs have poor water …

Hydroxypropyl methylcellulose acetate succinate (HPMCAS) has multi-disciplinary
applications spanning across the development of drug delivery systems, in 3D printing, and …

This study investigates the influence of drug load and polymer molecular weight on the
structure of tablets three-dimensionally (3D) printed from the binary mixture of prednisolone …

Abstract Curcumin (CUR), a polyphenol, is an attractive component of functional foods,
owing to various physiological activities. However, CUR is highly hydrophobic, insoluble in …

The aim of this research was to investigate three thermoanalytical techniques from the glass
transition temperature (Tg) determination point of view. In addition, the examination of the …

About 90% of active pharmaceutical ingredients (APIs) in the oral drug delivery system
pipeline have poor aqueous solubility and low bioavailability. To address this problem …