Wnt, a secreted glycoprotein, has an approximate molecular weight of 40 kDa, and it is a
cytokine involved in various biological phenomena including ontogeny, morphogenesis …

Osteoporosis is a worldwide disease characterized by reduction of bone mass and alteration
of bone architecture resulting in increased bone fragility and increased fracture risk. Causes …

Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

Bone marrow‐derived mesenchymal stem cells (BMMSC s) exhibit degenerative changes,
including imbalanced differentiation and reduced proliferation during aging, that contribute …

Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/
macrophage–lineage cells into the bone–resorbing cells called osteoclasts. Because …

Osteoporosis is a common disease that affects millions of patients worldwide and is most
common in menopausal women. The main characteristics of osteoporosis are low bone …

Rationale: The impaired function of endogenous bone marrow mesenchymal stem cells
(BMMSCs) is a determinant in the development of osteoporosis (OP). Recent researches …

Osteoporosis is the most common bone disease affecting millions of people worldwide,
particularly in elderly or in post-menopausal women. The pathogenesis is useful to …

Osteoporosis (OP), characterized by continuous bone loss and increased fracture risk, has
posed a challenge to patients and society. Long-term administration of current …

Hormones and mechanical loading co-regulate bone throughout the lifespan. In this review,
we posit that times of increased hormonal influence on bone provide opportunities for …