Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

M Kasravi, A Ahmadi, A Babajani… - Biomaterials …, 2023 - spj.science.org
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to
address the donor shortage as well as immunologic rejection attributed to cells in …

[HTML][HTML] Tissue engineering and regenerative medicine in pediatric urology: urethral and urinary bladder reconstruction

M Casarin, A Morlacco, F Dal Moro - International Journal of Molecular …, 2022 - mdpi.com
In the case of pediatric urology there are several congenital conditions, such as
hypospadias and neurogenic bladder, which affect, respectively, the urethra and the urinary …

[HTML][HTML] Three-dimensional neuroimmune co-culture system for modeling Parkinson's disease microenvironments in vitro

L Rueda-Gensini, JA Serna, D Rubio, JC Orozco… - …, 2023 - iopscience.iop.org
Parkinson's disease (PD) is a complex and multifaceted neurodegenerative disorder that
results from multiple environmental factors and multicellular interactions. Although several …

[HTML][HTML] A novel hybrid membrane for urinary conduit substitutes based on small intestinal submucosa coupled with two synthetic polymers

M Casarin, M Todesco, D Sandrin, F Romanato… - Journal of functional …, 2022 - mdpi.com
Among the urinary tract's malignancies, bladder cancer is the most frequent one: it is at the
tenth position of most common cancers worldwide. Currently, the gold standard therapy …

[HTML][HTML] The application of small intestinal submucosa in tissue regeneration

Y Zhao, H Peng, L Sun, J Tong, C Cui, Z Bai, J Yan… - Materials Today Bio, 2024 - Elsevier
The distinctive three-dimensional architecture, biological functionality, minimal
immunogenicity, and inherent biodegradability of small intestinal submucosa extracellular …

[HTML][HTML] A new detergent for the effective decellularization of bovine and porcine pericardia

M Todesco, SJ Imran, TM Fortunato, D Sandrin… - Biomimetics, 2022 - mdpi.com
Human and animal pericardia are among the most widely exploited materials suitable to
repair damaged tissues in the cardiovascular surgery context. Autologous, xenogeneic …

Hydrogel Derived from Decellularized Porcine Small Intestinal Submucosa as a Physical Shielding Repaired the Gut Epithelial Barrier of Murine Ulcerative Colitis

H Pan, B Ding, Z Jiang, J Wang, D Li… - Advanced Functional …, 2024 - Wiley Online Library
Ulcerative colitis (UC) is associated with the shedding of the gut mucus. Decellularized
porcine small intestinal submucosa (SIS‐ECM) contains numerous active forms of …

Silk fibroin bioscaffold from Bombyx mori and Antheraea assamensis elicits a distinct host response and macrophage activation paradigm in vivo and in vitro

G Janani, L Zhang, SF Badylak, BB Mandal - Biomaterials Advances, 2023 - Elsevier
Biomaterials composed of silk fibroin from both mulberry and non-mulberry silkworm
varieties have been investigated for their utility in tissue engineering and drug delivery, but …

The effect of crosslinking concentration, time, temperature and pH on the characteristic of genipin-crosslinked small intestinal submucosa

H Ji, Z Qiu, Y Wang, L Dong, J Cao, B Lian… - Materials Today …, 2022 - Elsevier
In an attempt to prepare genipin-crosslinked collagen scaffolds with different crosslinking
characteristics for experimental and clinical applications, the porcine small intestinal …

[HTML][HTML] Small intestinal submucosa-derived extracellular matrix as a heterotopic scaffold for cardiovascular applications

T Palmosi, AM Tolomeo, C Cirillo, D Sandrin… - … in Bioengineering and …, 2022 - frontiersin.org
Structural cardiac lesions are often surgically repaired using prosthetic patches, which can
be biological or synthetic. Amongst biological patches, in the current clinical scenario, those …