Pathogenetic mechanisms in radiation fibrosis

J Yarnold, MCV Brotons - Radiotherapy and oncology, 2010 - Elsevier
Deregulation of normal regenerative responses to physical, chemical and biological toxins
in susceptible individuals leads to abnormal remodelling of extracellular matrix with …

Spectrum of fibrosing diffuse parenchymal lung disease

AS Morgenthau, ML Padilla - … Journal of Medicine: A Journal of …, 2009 - Wiley Online Library
The interstitial lung diseases are a heterogeneous group of disorders characterized by
inflammation and/or fibrosis of the pulmonary interstitium. In 2002, the American Thoracic …

A controlled clinical trial with pirfenidone in the treatment of pathological skin scarring caused by burns in pediatric patients

J Armendariz-Borunda, I Lyra-Gonzalez… - Annals of plastic …, 2012 - journals.lww.com
Background: Pathologic skin scarring reversion remains a big challenge for surgeons, as
disfiguring scars have a dramatic influence on patient's quality of life. Methods: A controlled …

Resveratrol inhibits transforming growth factor-β–induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt …

E Fagone, E Conte, E Gili, M Fruciano… - Experimental lung …, 2011 - Taylor & Francis
The authors investigated the role of resveratrol (RV), a natural poliphenolic molecule with
several biological activities, in transforming growth factor-β (TGF-β)–induced proliferation …

Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate

SJ Lee, JH Park, JY Lee, YJ Jeong, JA Song… - Journal of Toxicologic …, 2016 - jstage.jst.go.jp
Although several animal models have been developed to study human pulmonary fibrosis,
lack of a perfect model has raised the need for various animal models of pulmonary fibrosis …

Presence of c-KIT–positive mast cells in obliterative bronchiolitis from diverse causes

NE Fuehrer, AM Marchevsky… - Archives of pathology & …, 2009 - meridian.allenpress.com
Context.—The mechanism of fibrosis is not clear in patients with obliterative bronchiolitis
after a remote injury. Immune-mediated progression may be a reason. c-KIT (CD117) …

小剂量糖皮质激素, N-乙酰半胱氨酸联合治疗特发性肺纤维化的前瞻性随机对照研究

杨雪梅, 王兴胜, 魏燕, 崔社怀 - 中华肺部疾病杂志(电子版), 2012 - cqvip.com
目的比较小剂量糖皮质激素+ N-乙酰半胱氨酸(NAC) 与NAC 单药治疗特发性肺纤维化(IPF)
的疗效和安全性. 方法选择2008 年3 月至2010 年9 月在我院就诊符合诊断标准及HRCT …

[HTML][HTML] Influence of a DNA-hsp65 vaccine on bleomycin-induced lung injury

AI Padua, CL Silva, SG Ramos, LH Faccioli… - Jornal Brasileiro de …, 2008 - SciELO Brasil
Objective: To evaluate the effects of immunization with a DNA-hsp65 vaccine in an
experimental model of pulmonary fibrosis. Methods: A total of 120 male C57BL/6 mice were …

经纤维支气管镜微导管治疗肺大咯血几种不同置入方法安全性的评价

卢晔, 崔会芳, 黄溢华, 林勇, 陈旭君 - 中华肺部疾病杂志: 电子版, 2012 - cqvip.com
目的探讨经纤维支气管镜微导管治疗肺大咯血几种不同置入方法的安全性. 方法总结我科2010
年10 月至2011 年12 月大咯血患者10 例, 均为男性, 通过对比观察手术过程难易程度, 耗费时间 …

Pharmacotherapy in patients with idiopathic pulmonary fibrosis

S Nagai, T Handa, DS Kim - Expert Opinion on Pharmacotherapy, 2008 - Taylor & Francis
Background: Based on the recognition of idiopathic pulmonary fibrosis as a fibroproliferative
disease with the usual interstitial pneumonia histology, pharmacotherapies should be …