Solid multifunctional granular bioink for constructing chondroid basing on stem cell spheroids and chondrocytes

L Zhang, H Tang, Z Xiahou, J Zhang, Y She… - …, 2022 - iopscience.iop.org
Stem cell spheroids are advanced building blocks to produce chondroid. However, the multi-
step operations including spheroids preparation, collection and transfer, the following 3D …

[HTML][HTML] Naphthoquinone Derivatives from Angustimassarina populi CF-097565 Display Anti-Tumour Activity in 3D Cultures of Breast Cancer Cells

TA Mackenzie, F Reyes, M Martínez… - Molecules, 2024 - mdpi.com
Cancer is one of the leading causes of death worldwide, with breast cancer being the
second cause of cancer-related mortality among women. Natural Products (NPs) are one of …

[HTML][HTML] High-throughput fabrication of cell spheroids with 3D acoustic assembly devices

T Miao, K Chen, X Wei, B Huang, Y Qian… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
Acoustic cell assembly devices are applied in cell spheroid fabrication attributed to their
rapid, label-free and low-cell damage production of size-uniform spheroids. However, the …

[HTML][HTML] A vascularized in vivo melanoma model suitable for metastasis research of different tumor stages using fundamentally different bioinks

R Schmid, SK Schmidt, S Schrüfer, DW Schubert… - Materials Today Bio, 2024 - Elsevier
Although 2D cancer models have been the standard for drug development, they don't
resemble in vivo properties adequately. 3D models can potentially overcome this …

[HTML][HTML] Disruptive 3D in vitro models for respiratory disease investigation: A state-of-the-art approach focused on SARS-CoV-2 infection

ML Seixas, CS Bartolomeo, R Lemes… - Biomaterials and …, 2023 - Elsevier
COVID-19, along with most respiratory diseases in the medical field, demonstrates
significant ability to take its toll on global population. There is a particular difficulty in …

Enhancement of lacrimal gland cell function by decellularized lacrimal gland derived hydrogel

KEWB Zakour, S Kaya, JC Matros, MC Hacker… - …, 2024 - iopscience.iop.org
Sustainable treatment of aqueous deficient dry eye (ADDE) represents an unmet medical
need and therefore requires new curative and regenerative approaches based on …

Microfabrication methods for 3D spheroids formation and their application in biomedical engineering

S Ahn, D Kim, K Cho, WG Koh - Korean Journal of Chemical Engineering, 2023 - Springer
Three-dimensional cell culture systems offer greater understanding of the complex human
body structure than monolayer cell cultures. Spheroids, which are the most useful and …

High-Resolution In Situ High-Content Imaging of 3D-Bioprinted Single Breast Cancer Spheroids for Advanced Quantification of Benzo(a)pyrene Carcinogen-Induced …

S Hong, JM Song - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Cancer stem cells (CSCs), also known as tumor-initiating cells, are critically correlated with
carcinogenesis and are strongly affected by the environmental factors. Environmental …

[HTML][HTML] Tools for manipulation and positioning of microtissues

E Vuille-dit-Bille, DV Deshmukh, S Connolly, S Heub… - Lab on a Chip, 2022 - pubs.rsc.org
Complex three-dimensional (3D) in vitro models are emerging as a key technology to
support research areas in personalised medicine, such as drug development and …

Embedded bioprinted multicellular spheroids modeling pancreatic cancer bioarchitecture towards advanced drug therapy

X Wei, Y Wu, K Chen, L Wang, M Xu - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
The desmoplastic bioarchitecture and microenvironment caused by fibroblasts have been
confirmed to be closely related to the drug response behavior of pancreatic ductal …