The COVID-19 pandemic caused by the SARS-CoV-2 virus, overlaps with the ongoing
epidemics of cigarette smoking and electronic cigarette (e-cig) vaping. However, there is …

Vascular endothelial cells line the inner surface of the entire cardiovascular system as a
single layer and are involved in an impressive array of functions, ranging from the regulation …

Inflammatory bowel disease (IBD) is an idiopathic intestinal inflammatory disease, including
ulcerative colitis (UC) and Crohn's disease (CD). The abnormality of inflammatory and …

Cerebral ischemic injury is a leading cause of death and long-term disability throughout the
world. Peroxisome proliferator-activated receptor gamma (PPAR-ɣ) is a ligand-activated …

Periodontitis is closely related to oral cancer, but the molecular mechanism of periodontal
pathogens involved in the occurrence and development of oral cancer is still inconclusive …

The clinical success of the two BTK inhibitors, ibrutinib and acalabrutinib, represents a major
breakthrough in the treatment of chronic lymphocytic leukemia (CLL) and has also …

Pyroptosis is a recently identified type of lytic programmed cell death, in which pores form in
the plasma membrane, and cells swell, rupture, and then release their contents, including …

Atherosclerosis is an early pathological basis of numerous cardiovascular events that result
in death or disability. Recent studies have described PCSK9 as a novel target for the …

The cytosolic pattern recognition receptor NLRP3 senses host-derived danger signals and
certain microbe-derived products in both humans and rodents. NLRP3 activation assembles …

Abstract Benzo (a) pyrene [B (a) P], a ubiquitous environmental pollutant, causes lung
inflammatory damage. Pyroptosis, a new inflammation-dependent programmed cell death …