Immunosenescence is a series of age-related changes that affect the immune system and,
with time, lead to increased vulnerability to infectious diseases. This Review addresses …

As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches.
Given that the elderly population is dramatically increasing and that aging is the greatest risk …

The number of scientific publications on frailty has been increasing exponentially during the
past 15 years (Fig. 1). Studies on the topic are not limited to the geriatric and gerontology …

Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …

Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

Comparison of Risk and Age at Diagnosis of Myocardial Infarction, End-Stage Renal Disease,
and Non-AIDS-Defining Cancer in HIV-Infected Versus Uninfected Adults | Clinical Infectious …

Objective Post-traumatic stress disorder (PTSD) has major public health significance.
Evidence that PTSD may be associated with premature senescence (early or accelerated …

With the wider availability of antiretrovirals, the world's HIV population is aging. More than
10% of the 34.5 million HIV-positive individuals worldwide are over the age of 50 years and …

Immunosenescence involves age-related remodeling changes in the organization of
lymphoid organs and functionality of immune cells, which have been associated with …