Practical Guidance for Developing Small-Molecule Optical Probes for In Vivo Imaging

C Ran, JR Mansfield, M Bai, NT Viola… - Molecular Imaging and …, 2023 - Springer
Abstract The WMIS Education Committee (2019–2022) reached a consensus that white
papers on molecular imaging could be beneficial for practitioners of molecular imaging at …

Activatable small molecular luminescence probes for autofluorescence-free bioimaging

X Sun, L Xu, X Liu, HD Xu, W Zhan, G Liang - TrAC Trends in Analytical …, 2023 - Elsevier
Autofluorescence-free luminescence imaging, which captures optical output without using
real-time light excitation, enables non-invasive visualization of biological events with …

[HTML][HTML] Firefly luciferase offers superior performance to AkaLuc for tracking the fate of administered cell therapies

F Amadeo, A Plagge, A Chacko, B Wilm… - European Journal of …, 2022 - Springer
Introduction A novel, red-shifted bioluminescence imaging (BLI) system called AkaBLI has
been recently developed for cell tracking in preclinical models and to date, limited data is …

[HTML][HTML] Quantitative assessment on optical properties as a basis for bioluminescence imaging: an experimental and numerical approach to the transport of optical …

T Karstens, T Staufer, R Buchin, F Grüner - Sensors, 2023 - mdpi.com
Bioluminescence imaging (BLI) is a widely used technique in preclinical scientific research,
particularly in the development of mRNA-based medications and non-invasive tumor …

[HTML][HTML] Coelenterazine-Type Bioluminescence-Induced Optical Probes for Sensing and Controlling Biological Processes

T Jiang, J Song, Y Zhang - International Journal of Molecular Sciences, 2023 - mdpi.com
Bioluminescence-based probes have long been used to quantify and visualize biological
processes in vitro and in vivo. Over the past years, we have witnessed the trend of …

[HTML][HTML] Bioluminescent and fluorescent proteins: molecular mechanisms and modern applications

ES Vysotski - International Journal of Molecular Sciences, 2022 - mdpi.com
Light emission by living organisms in the visible spectrum range is called bioluminescence.
Despite the fact that luminous organisms are found among terrestrial species (bacteria …

A Comprehensive Exploration of Bioluminescence Systems, Mechanisms, and Advanced Assays for Versatile Applications

AN Dunuweera, SP Dunuweera… - Biochemistry …, 2024 - Wiley Online Library
Bioluminescence has been a fascinating natural phenomenon of light emission from living
creatures. It happens when the enzyme luciferase facilitates the oxidation of luciferin …

Bioluminescence imaging using d-luciferin and its analogs for visualizing Bdnf expression in living mice; different patterns of bioluminescence signals using distinct …

M Fukuchi, S Mitazaki, R Saito-Moriya… - The Journal of …, 2022 - academic.oup.com
Brain-derived neurotrophic factor (BDNF) plays a crucial role in numerous brain functions,
including memory consolidation. Previously, we generated a Bdnf-Luciferase transgenic …

Expedient Synthesis and Characterization of π-Extended Luciferins

DR Caldwell, KM Townsend… - The Journal of …, 2023 - ACS Publications
Bioluminescence imaging enables the sensitive tracking of cell populations and the
visualization of biological processes in living systems. Bioluminescent luciferase/luciferin …

Quantum yield of near-infrared bioluminescence with firefly luciferin analog: AkaLumine

R Ono, K Osawa, Y Takahashi, Y Noguchi… - … of Photochemistry and …, 2023 - Elsevier
We investigated bioluminescence with d-AkaLumine, which is a firefly luciferin analog
producing 675-nm light through chemical reaction with O 2, ATP, and Mg 2+ in native firefly …