Ubiquitination is a highly conserved and fundamental posttranslational modification (PTM) in
all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) …

Azacitidine and decitabine are hypomethylating agents that have dose‐dependent
epigenetic and cytotoxic effects and are widely used in the treatment of myelodysplastic …

Summary Myelodysplastic/myeloproliferativeneoplasms (MDS/MPN) areagroupof
myeloidneoplasms withoverlappingofmyelodysplasticsyndrome (MDS) and …

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with
overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative …

Simple Summary Chronic myelomonocytic leukemia (CMML) is an infrequent disease with
poor prognosis and risk of progression into acute myeloid leukemia (AML). Stem cell …

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell malignancy,
and allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is the only curable …

Simple Summary Plasmacytoid dendritic cells are the main type I interferon producing cells
in humans and are able to modulate innate and adaptive immune responses. Tumor …

Although CMML since long has been separated from MDS, many studies continue to
evaluate the outcomes of both diseases after hematopoietic cell transplantation (allo‐HCT) …

Myelodysplastic syndromes (MDS) are acquired clonal stem cell disorders exhibiting
ineffective hematopoiesis, dysplastic cell morphology in the bone marrow, and peripheral …

Chronic myelomonocytic leukemia (CMML) is a heterogeneous disease presenting with
either myeloproliferative or myelodysplastic features. Allogeneic hematopoietic cell …