Human OMICs and computational biology research in Africa: current challenges and prospects
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …
Genetic evidence and historical theories of the Asian and African origins of the present Malagasy population
M Heiske, O Alva, V Pereda-Loth… - Human molecular …, 2021 - academic.oup.com
The origin of the Malagasy population has been a subject of speculation since the 16th
century. Contributions of African, Asian, Indian, Melanesian, Arabic and Persian populations …
century. Contributions of African, Asian, Indian, Melanesian, Arabic and Persian populations …
Genomic landscape of human diversity across Madagascar
D Pierron, M Heiske… - Proceedings of the …, 2017 - National Acad Sciences
Although situated∼ 400 km from the east coast of Africa, Madagascar exhibits cultural,
linguistic, and genetic traits from both Southeast Asia and Eastern Africa. The settlement …
linguistic, and genetic traits from both Southeast Asia and Eastern Africa. The settlement …
Mitochondrial DNA and the Y chromosome suggest the settlement of Madagascar by Indonesian sea nomad populations
Background Linguistic, cultural and genetic characteristics of the Malagasy suggest that both
Africans and Island Southeast Asians were involved in the colonization of Madagascar …
Africans and Island Southeast Asians were involved in the colonization of Madagascar …
Malagasy genetic ancestry comes from an historical Malay trading post in Southeast Borneo
Malagasy genetic diversity results from an exceptional protoglobalization process that took
place over a thousand years ago across the Indian Ocean. Previous efforts to locate the …
place over a thousand years ago across the Indian Ocean. Previous efforts to locate the …
Genetic structure and sex‐biased gene flow in the history of southern African populations
Objectives We investigated the genetic history of southern African populations with a special
focus on their paternal history. We reexamined previous claims that the Y‐chromosome …
focus on their paternal history. We reexamined previous claims that the Y‐chromosome …
The Comoros show the earliest Austronesian gene flow into the Swahili corridor
At the dawn of the second millennium, the expansion of the Indian Ocean trading network
aligned with the emergence of an outward-oriented community along the East African coast …
aligned with the emergence of an outward-oriented community along the East African coast …
Contrasting linguistic and genetic origins of the Asian source populations of Malagasy
The Austronesian expansion, one of the last major human migrations, influenced regions as
distant as tropical Asia, Remote Oceania and Madagascar, off the east coast of Africa. The …
distant as tropical Asia, Remote Oceania and Madagascar, off the east coast of Africa. The …
Carriers of human mitochondrial DNA macrohaplogroup M colonized India from southeastern Asia
P Marrero, KK Abu-Amero, JM Larruga… - BMC Evolutionary …, 2016 - Springer
Background From a mtDNA dominant perspective, the exit from Africa of modern humans to
colonize Eurasia occurred once, around 60 kya, following a southern coastal route across …
colonize Eurasia occurred once, around 60 kya, following a southern coastal route across …
Genome analysis using whole-exome sequencing of non-syndromic cleft lip and/or palate from Malagasy trios identifies variants associated with Cilium-related …
Background: Orofacial clefts (OFCs) are common congenital disabilities that can occur as
isolated non-syndromic events or as part of Mendelian syndromes. OFC risk factors vary due …
isolated non-syndromic events or as part of Mendelian syndromes. OFC risk factors vary due …