Major advances in chronic heart failure (cHF) therapy have been achieved and documented
in adult patients, while research regarding the mechanisms and therapy of cHF in children …

Aim: Infants with congenital heart disease and left-to-right shunts may develop significant
clinical symptoms of congestive heart failure in spite of therapy with digoxin and diuretics …

During the last decades, the introduction of new, more efficient drugs, has significantly
improved the heart failure (HF) therapy of adults. Therapeutic focus has shifted from simple …

Chronic heart failure (CHF) in children occurs mostly as a result of systolic dysfunction of the
systemic ventricle or of congenital defects leading to large left-to-right shunts and pulmonary …

Contraindications to the use of digoxin include hypertrophic obstructive cardiomyopathy,
antidromic tachycardia through accessory bypass tracts in Wolff-Parkinson-White syndrome …

The treatment of children with medicinal products is an important scientific area. It is
recognized that many medicines that are used extensively in pediatric patients are either …

Isolated ventricular septal defect (VSD) is the most common congenital cardiac
malformation. VSD is also the most frequent defect associated to others congenital …

Large ventricular septal defects account for important clinical problems during infancy,
notably congestive heart failure. Timing of clinical presentation is dependent on the rapidity …

Introduction Infants with single ventricle congenital heart disease are vulnerable to
complications between stage 1 and stage 2 of palliation. Pharmaceutical treatment during …

Pharmacologic therapy represents the mainstay of treatment for heart failure in children.
However, medical therapy for this population is not widely standardized. This is mainly due …