Cutaneous melanoma

HK Koh - New England Journal of Medicine, 1991 - Mass Medical Soc
CUTANEOUS melanoma has become a common form of cancer. 1 Decades of steady
increases in the incidence and mortality rates of cutaneous malignant melanoma have …

A Comprehensive Review of Various Therapeutic Strategies for the Management of Skin Cancer

SR Dachani, M Kaleem, MA Mujtaba, N Mahajan… - ACS …, 2024 - ACS Publications
Skin cancer (SC) poses a global threat to the healthcare system and is expected to increase
significantly over the next two decades if not diagnosed at an early stage. Early diagnosis is …

Zyflamend, a polyherbal mixture, down regulates class I and class II histone deacetylases and increases p21 levels in castrate-resistant prostate cancer cells

EC Huang, Y Zhao, G Chen, SJ Baek… - … and alternative medicine, 2014 - Springer
Background Zyflamend, a mixture containing extracts of ten herbs, has shown promise in a
variety of preclinical cancer models, including prostate cancer. The current experiments …

Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer …

AF MacDonald, A Bettaieb, DR Donohoe… - … and alternative medicine, 2018 - Springer
Background Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using
preclinical models of castrate-resistant prostate cancer mediated in part by 5′-adenosine …

Metabolomics approach in the study of the well-defined Polyherbal preparation Zyflamend

ED Tague, AK Bourdon, A MacDonald… - Journal of medicinal …, 2018 - liebertpub.com
Zyflamend is a highly controlled blend of 10 herbal extracts that synergistically impact
multiple cell signaling pathways with anticancer and anti-inflammatory properties. More …

[HTML][HTML] Zyflamend, a polyherbal mixture, inhibits lipogenesis and mTORC1 signalling via activation of AMPK

Y Zhao, D Donohoe, EC Huang, J Whelan - Journal of Functional Foods, 2015 - Elsevier
A select blend of herbal extracts, Zyflamend, inhibits tumour growth via multiple mechanisms
that arise through synergistic interactions between individual components. The objective in …

[HTML][HTML] Restoring trail induced apoptosis using naturopathy. Hercules joins hand with nature to triumph over lernaean hydra

AA Farooqi, CD Gadaleta, G Ranieri, S Fayyaz… - Current …, 2017 - ncbi.nlm.nih.gov
Cancer is a multifaceted disease. Our deepened knowledge about genetic and biological
mechanisms of cancer cells presents an opportunity to explore the inter-individual …

Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway

Y Xue, L Yang, J Li, Y Yan, Q Jiang, L Shen… - OncoTargets and …, 2018 - Taylor & Francis
Background Cisplatin-based chemotherapy is mainstay treatment in urinary bladder cancer
(UBC). However, tumor recurrence frequently occurs with the acquisition of cisplatin …

Zyflamend induces apoptosis in pancreatic cancer cells via modulation of the JNK pathway

DL Puckett, M Alquraishi, D Alani, S Chahed… - Cell Communication and …, 2020 - Springer
Background Current pharmacological therapies and treatments targeting pancreatic
neuroendocrine tumors (PNETs) have proven ineffective, far too often. Therefore, there is an …

Isoamylamine Induces B16-F1 Melanoma Cell Autophagy by Upregulating the 5′ Adenosine Monophosphate-Activated Protein Pathway

YC Peng, SR Wang, YF Lai, NM Tsai, KL Lin… - Journal of Medicinal …, 2021 - liebertpub.com
Isoamylamine (IA) is an aliphatic monoamine molecule present in cheese, eggs, and wine. It
belongs to the family of polyamines and also can be synthesized endogenously. It has been …