The chemistry of reticular framework nanoparticles: MOF, ZIF, and COF materials

E Ploetz, H Engelke, U Lächelt… - Advanced Functional …, 2020 - Wiley Online Library
Nanoparticles have become a vital part of a vast number of established processes and
products; they are used as catalysts, in cosmetics, and even by the pharmaceutical industry …

[HTML][HTML] Current strategies in assessment of nanotoxicity: alternatives to in vivo animal testing

HJ Huang, YH Lee, YH Hsu, CT Liao, YF Lin… - International journal of …, 2021 - mdpi.com
Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

[HTML][HTML] Adjuvant probiotics of Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 attenuate …

CH Wang, HR Yen, WL Lu, HH Ho, WY Lin… - Frontiers in …, 2022 - frontiersin.org
Introduction Type 1 diabetes mellitus (T1DM) is characterized by autoimmune destruction of
pancreatic β cells. Previous study has discovered that probiotic strains residing in the gut …

[HTML][HTML] Graphene oxide containing self-assembling peptide hybrid hydrogels as a potential 3D injectable cell delivery platform for intervertebral disc repair …

C Ligorio, M Zhou, JK Wychowaniec, X Zhu, C Bartlam… - Acta biomaterialia, 2019 - Elsevier
Cell-based therapies have shown significant promise in tissue engineering with one key
challenge being the delivery and retention of cells. As a result, significant efforts have been …

[HTML][HTML] Scalable continuous-flow electroporation platform enabling T cell transfection for cellular therapy manufacturing

JA VanderBurgh, TN Corso, SL Levy… - Scientific Reports, 2023 - nature.com
Viral vectors represent a bottleneck in the manufacturing of cellular therapies.
Electroporation has emerged as an approach for non-viral transfection of primary cells, but …

[HTML][HTML] Smart polymers for cell therapy and precision medicine

HJ Huang, YL Tsai, SH Lin, S Hsu - Journal of biomedical science, 2019 - Springer
Soft materials have been developed very rapidly in the biomedical field over the past 10
years because of advances in medical devices, cell therapy, and 3D printing for precision …

Engineering the surface of therapeutic “living” cells

J Park, B Andrade, Y Seo, MJ Kim… - Chemical …, 2018 - ACS Publications
Biological cells are complex living machines that have garnered significant attention for their
potential to serve as a new generation of therapeutic and delivery agents. Because of their …

[HTML][HTML] Self-assembling peptide hydrogels as functional tools to tackle intervertebral disc degeneration

C Ligorio, JA Hoyland, A Saiani - Gels, 2022 - mdpi.com
Low back pain (LBP), caused by intervertebral disc (IVD) degeneration, is a major
contributor to global disability. In its healthy state, the IVD is a tough and well-hydrated …

Investigational treatments for epidermolysis bullosa

PC Hou, HT Wang, S Abhee, WT Tu… - American Journal of …, 2021 - Springer
Epidermolysis bullosa (EB) is a heterogeneous group of rare inherited blistering skin
disorders characterized by skin fragility following minor trauma, usually present since birth …

[HTML][HTML] Antifreeze proteins: Novel applications and navigation towards their clinical application in cryobanking

MD Ekpo, J Xie, Y Hu, X Liu, F Liu, J Xiang… - International Journal of …, 2022 - mdpi.com
Antifreeze proteins (AFPs) or thermal hysteresis (TH) proteins are biomolecular gifts of
nature to sustain life in extremely cold environments. This family of peptides, glycopeptides …