Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

Antivenom preclinical efficacy testing against Asian snakes and their availability in Asia: A systematic review

S Soopairin, C Patikorn, S Taychakhoonavudh - PloS one, 2023 - journals.plos.org
Background Cross-neutralizing strategy has been applied to improve access to antivenoms,
a key to reducing mortality and disability of snakebite envenoming. However, preclinical …

Snake Venomics and Antivenomics of Cape Cobra (Naja nivea) from South Africa: Insights into Venom Toxicity and Cross-Neutralization Activity

CH Tan, KY Wong, LK Huang, KY Tan, NH Tan… - Toxins, 2022 - mdpi.com
Naja nivea (Cape Cobra) is endemic to southern Africa. Envenoming by N. nivea is
neurotoxic, resulting in fatal paralysis. Its venom composition, however, has not been …

Immunoreactivity and neutralization efficacy of Pakistani Viper Antivenom (PVAV) against venoms of Saw-scaled Vipers (Echis carinatus subspp.) and Western …

ASS Lim, KY Tan, CH Tan - Acta Tropica, 2024 - Elsevier
Snakebite envenoming (SBE) is a priority Neglected Tropical Disease listed by the World
Health Organization. South Asia is heavily affected, and virtually all countries in the region …

Bungarus fasciatus venom from eastern and north-east India: venom variation and immune cross-reactivity with Indian polyvalent antivenoms

A Talukdar, A Malhotra, HT Lalremsanga… - Journal of Proteins and …, 2023 - Springer
Bungarus fasciatus is one of the medically important elapid snakes of South and South-
eastern Asia and is responsible for several snakebite incidents some of which were fatal. In …

Clinical study of anti-snake venom blockade in the treatment of local tissue necrosis caused by Chinese cobra (Naja atra) bites

L Zeng, J Hou, C Ge, Y Li, J Gao, C Zhang… - PLOS Neglected …, 2022 - journals.plos.org
Objective This study aimed to evaluate the clinical therapeutic efficacy of anti-snake venom
serum blockade in treating local tissue necrosis caused by Chinese cobra (Naja atra) bites …

The Effect of Australian and Asian Commercial Antivenoms in Reversing the Post-Synaptic Neurotoxicity of O. hannah, N. naja and N. kaouthia Venoms In Vitro

TM Huynh, WC Hodgson, GK Isbister, A Silva - Toxins, 2022 - mdpi.com
Despite antivenoms being the only established specific treatment for neuromuscular
paralysis arising from snake envenoming, their ability to reverse the post-synaptic …

Isolation and Characterization of Two Postsynaptic Neurotoxins From Indian Cobra (Naja Naja) Venom

TM Huynh, A Silva, GK Isbister… - Frontiers in …, 2022 - frontiersin.org
The Indian Cobra (Naja naja) is among the “Big Four” responsible for most of the snakebite
envenoming cases in India. Although recent proteomic studies suggest the presence of …

[PDF][PDF] Studies on Bungarus fasciatus venom from Eastern and North-East India and characterization of poorly immunodepleted PLA2 enzymes

A Talukdar - 2024 - agnee.tezu.ernet.in
Kraits belong to the genus Bungarus which form an important group of snakes in India
(around 12 to 14 known species) and belong to the Elapidae family. One of these kraits …

Habitat, ecology, and venom variation of cobras (genus Naja) and other venomous snakes of Bangladesh

MAW Chowdhury - 2022 - edoc.hu-berlin.de
Snakes are threatened by habitat degradation and anthropogenic impacts, while accidental
encounters between humans and snakes may result in snakebite incidents. Thus, the …