Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials

H Zhang, X Yue, Z Chen, C Liu, W Wu, N Zhang, Z Liu… - Molecular Cancer, 2023 - Springer
Despite centuries since the discovery and study of cancer, cancer is still a lethal and
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …

The role of cancer-associated fibroblasts in bladder cancer progression

L Huang, Q Xie, J Deng, WF Wei - Heliyon, 2023 - cell.com
Cancer-associated fibroblasts (CAFs) are key stromal cells in the tumor microenvironment
(TME) that critically contribute to cancer initiation and progression. In bladder cancer (BCa) …

[PDF][PDF] 肿瘤相关成纤维细胞在膀胱癌发生发展中的研究进展

叶峻江, 吴睿成, 李登雄, 韩平 - 临床泌尿外科杂志, 2023 - lcmwen.whuhzzs.com
肿瘤相关成纤维细胞作为肿瘤微环境中主要的间质细胞, 可以通过改造肿瘤微环境,
影响肿瘤的发生发展. 膀胱癌是泌尿系统最常见的恶性肿瘤之一, 具有易复发, 易进展的特点 …

CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck squamous cell carcinoma growth

J Gao, Z Wang, S Lin, Y Tian, H Wu, Z Li, F Liu - Cellular Signalling, 2024 - Elsevier
Objective CC motif chemokine receptor 7 (CCR7) significantly influences tumors onset and
progression, yet its impact on the tumor microenvironment (TME) and specific mechanisms …

[HTML][HTML] Integrating single-cell RNA-seq to identify fibroblast-based molecular subtypes for predicting prognosis and therapeutic response in bladder cancer

J Wang, Z Tan, Y Huang, C Li, P Zhan, H Wang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Bladder cancer (BLCA) is a highly aggressive and heterogeneous disease,
posing challenges for diagnosis and treatment. Cancer immunotherapy has recently …

In silico analysis and validation the cancer-associated fibroblasts related gene CAMK4 promotes bladder cancer progression

X Su, Y Guo, Y Li - 2024 - researchsquare.com
Background: Cancer-associated fibroblasts (CAFs) are crucial in the regulation of cancer
cell biological properties through complex and dynamic communication networks. However …

Research progress of tumor-associated fibroblasts in the genesis and development of bladder cancer

YE Junjiang, WU Ruicheng, LI Dengxiong… - J Clin …, 2023 - lcmwen.whuhzzs.com
Cancer-associated fibroblasts, as the main stromal cells in the tumor microenvironment, can
affect the genesis and development of tumors by modifying the tumor microenvironment …