Hypertension is a risk factor for the development of end-stage renal disease. The
mechanisms underlying hypertensive nephropathy are poorly understood. There is …

The phrase reactive oxygen species covers a number of molecules and atoms, including the
quintessential member of the group, O2−; singlet oxygen; H2O2; organic peroxides; and …

Cyclosporine A (CsA) nephrotoxicity underweighs the therapeutic benefits of such a
powerful immunosuppressant. Whether oxidative stress plays a role in such toxicity is not …

Type 2 diabetes mellitus (T2DM) is a metabolic disease accompanied by a series of
diseases such as diabetic nephropathy. The drug pair (HS) of Astragalus Radix (HQ) and …

Renal ischemia–reperfusion injury occurs in many clinical conditions such as hypovolemic
shock, thromboembolism, injury and after renal transplantation. Under these conditions …

Aims. The purpose of the study was to investigate the differences of adenosine, adenine,
inosine, xanthine, hypoxanthine, and uric acid concentrations in patients with type 2 …

BACKGROUND: The aim of this study was to investigate the correlation between plasma
and tissue oxidative stress and the antioxidative response, by measuring malon dialdehyde …

Background: Cyclosporine A (CsA) is the first-line immunosuppressant employed for the
management of solid organ transplantation and autoimmune diseases. Nephrotoxicity is the …

Cyclosporine A (CsA) is one of the first line immunosuppressants employed in the
management of solid organ transplantation and autoimmune diseases. The clinical utility of …

OBJECTIVES: The assessment of the clinical significance of adenosine, adenine, inosine,
xanthine, hypoxanthine and uric acid concentrations in patients with type 2 diabetes mellitus …