Influx of sodium ions through voltage-gated sodium channels in cardiomyocytes is essential
for proper electrical conduction within the heart. Both acquired conditions associated with …

Cardiac macrophages represent a functionally diverse population of cells involved in
cardiac homeostasis, repair, and remodeling. With recent advancements in single-cell …

Acute myocardial infarction is one of the most important causes of death in the world,
causing a huge health and economic burden to the world. It is still a ticklish problem how to …

Heart disease, as well as systemic metabolic alterations, can leave a 'fingerprint'of structural
and functional changes in the atrial myocardium, leading to the onset of atrial …

Highlights What are the main findings? Abnormally increased concentrations of ingested or
inhaled pollutants can lead to cardiac oxidative stress and inflammation. Untreated cardiac …

Cardiac conduction abnormalities are disorders in metabolic syndrome (MetS), however,
their mechanisms are unknown. Although ventricular arrhythmia reflects the changes in QT …

Myocardial infarction (MI) induces structural and electrical cardiac remodeling in response to
ischemic insult, causing lethal arrhythmias and sudden death. Progranulin (PGRN) is a …

Background A biological mechanism called inflammation is necessary for reacting to
damaging stimuli, but it can also, ironically, play a role in the formation of arrhythmias, or the …

ARTICLES DISCUSSED: Tomsits, P., Schuttler, D., Kaab, S., Clauss, S., Voigt, N. Isolation of
high quality murine atrial and ventricular myocytes for simultaneous measurements of Ca2+ …

Metabolic syndrome (MetS) has impact on arrhythmia pathogenesis includes changes in QT-
interval, reflecting time-course of ventricular myocyte action potentials (APs), while long or …