Background Myeloid-derived suppressor cells (MDSCs) are evolving as a prominent
determinant in cancer occurrence and development and are functionally found to suppress T …

Background Clinically, some patients whose HBsAg becomes negative owing to antiviral
therapy or spontaneously still show a low level of HBV DNA persistence in serum. T …

Objective The aims of this study were to investigate the kinetic changes of serum, virological,
and immunological markers during entecavir (ETV) antiviral therapy and to explore whether …

Protein three-dimensional structural analysis using artificial intelligence is attracting
attention in various fields, such as the estimation of vaccine structure and stability. In …

Aims Study of clinical characteristics of hepatitis B virus deoxyribonucleic acid (HBV DNA)-
negative, hepatitis B surface antigen (HBsAg)-positive, hepatitis B e antigen (HBeAg) …

Background This study was the first to examine the association of baseline clinical factors
with the rate of HBsAg clearance in a large retrospective cohort of Chinese patients with …

Chronic hepatitis B (CHB) is one of the most serious infectious diseases in China (1, 2). CHB
is considered to be an immune-mediated disease, in which the immune response initiated …

Background At present, the clinical research on OBI patients is still insufficient. Cytokines are
small molecular proteins with immune regulation and immune effects, and are important …

Aim: To explore clinical features of HCC in HBsAg-serocleared patients; to identify risk
factors associated with postoperative recurrence after curative hepatectomy; and to compare …