Development of Methods for the Determination of pKa Values

J Reijenga, A Van Hoof, A Van Loon… - Analytical chemistry …, 2013 - journals.sagepub.com
The acid dissociation constant (pKa) is among the most frequently used physicochemical
parameters, and its determination is of interest to a wide range of research fields. We …

[HTML][HTML] Influence of various factors on caffeine content in coffee brews

E Olechno, A Puścion-Jakubik, ME Zujko, K Socha - Foods, 2021 - mdpi.com
Coffee brews are one of the most popular drinks. They are consumed for caffeine and its
stimulant properties. The study aimed to summarize data on the influence of various factors …

Holistic Prediction of the pKa in Diverse Solvents Based on a Machine‐Learning Approach

Q Yang, Y Li, JD Yang, Y Liu, L Zhang… - Angewandte …, 2020 - Wiley Online Library
While many approaches to predict aqueous pKa values exist, the fast and accurate
prediction of non‐aqueous pKa values is still challenging. Based on the iBonD experimental …

Effect of transpiration on plant accumulation and translocation of PPCP/EDCs

LK Dodgen, A Ueda, X Wu, DR Parker, J Gan - Environmental Pollution, 2015 - Elsevier
The reuse of treated wastewater for agricultural irrigation in arid and hot climates where
plant transpiration is high may affect plant accumulation of pharmaceutical and personal …

An investigation into Sunitinib malate nanoparticle production by US-RESOLV method: Effect of type of polymer on dissolution rate and particle size distribution

F Razmimanesh, G Sodeifian, SA Sajadian - The Journal of Supercritical …, 2021 - Elsevier
The present study practiced ultrasonic-assisted rapid expansion of a supercritical CO 2
solution into a liquid solvent (US-RESOLV) process for the synthesis of nanoparticles (NPs) …

Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds

L Settimo, K Bellman, RMA Knegtel - Pharmaceutical research, 2014 - Springer
Purpose Assessment of the accuracy of experimental and theoretical methods of pKa
determination for acids and bases as separate classes. Methods Four literature pKa …

Comparison of Nine Programs Predicting pKa Values of Pharmaceutical Substances

C Liao, MC Nicklaus - Journal of chemical information and …, 2009 - ACS Publications
Knowledge of the possible ionization states of a pharmaceutical substance, embodied in the
p K a values (logarithm of the acid dissociation constant), is vital for understanding many …

A low cost, bulk synthesis of the thermally reduced graphene oxide in an aqueous solution of sulphuric acid & hydrogen peroxide via electrochemical method

PK Singh, K Sharma, PK Singh - Inorganic Chemistry Communications, 2022 - Elsevier
The electrochemical approach is considered the simplest, most environmentally friendly, low-
cost, and bulk synthesis route from graphite. The proposed approach is based upon the low …

Electrochemical synthesis and characterization of thermally reduced graphene oxide: Influence of thermal annealing on microstructural features

PK Singh, PK Singh, K Sharma - Materials Today Communications, 2022 - Elsevier
Controlling the overall microstructure of graphene oxide (GO), which influences its
properties (grain size, structural disorder, degree of oxygen functions, thermal stability, and …

Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs

A Shapira, YG Assaraf, YD Livney - Nanomedicine in Cancer, 2017 - api.taylorfrancis.com
28.1 Methods Mitoxantrone dihydrochloride (MX; M6545; purity> 97% by HPLC) and β-CN
from bovine milk (C6905; 90% purity) were purchased from Sigma-Aldrich Ltd.(Rehovot …