Multimorbidity and functional impairment–bidirectional interplay, synergistic effects and common pathways

A Calderón‐Larrañaga, DL Vetrano… - Journal of internal …, 2019 - Wiley Online Library
This review discusses the interplay between multimorbidity (ie co‐occurrence of more than
one chronic health condition in an individual) and functional impairment (ie limitations in …

Polypharmacy management in older patients

RW Hoel, RMG Connolly, PY Takahashi - Mayo Clinic Proceedings, 2021 - Elsevier
Medications to treat disease and extend life in our patients often amass in quantities,
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …

Cost of prescription drug–related morbidity and mortality

JH Watanabe, T McInnis… - Annals of …, 2018 - journals.sagepub.com
Background: Public attention and recent US Congressional activity has intensified focus on
escalating medication prices. However, the actual cost of medication use extends beyond …

Predicting risk of adverse drug reactions in older adults

AH Lavan, P Gallagher - Therapeutic advances in drug …, 2016 - journals.sagepub.com
Adverse drug reactions (ADRs) are common in older adults, with falls, orthostatic
hypotension, delirium, renal failure, gastrointestinal and intracranial bleeding being amongst …

KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease

PE Stevens, SB Ahmed, JJ Carrero… - Kidney …, 2024 - kidney-international.org
This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …

Polypharmacy and medication management in older adults

J Kim, AL Parish - Nursing Clinics, 2017 - nursing.theclinics.com
Although prescribed and over-the-counter medications may improve a wide range of health
problems, they also may cause or contribute to harm, especially in older adults. Current-day …

[HTML][HTML] Factors affecting the development of adverse drug reactions

MJ Alomar - Saudi pharmaceutical journal, 2014 - Elsevier
Objectives To discuss the effect of certain factors on the occurrence of Adverse Drug
Reactions (ADRs). Data Sources A systematic review of the literature in the period between …

[HTML][HTML] Pharmacokinetic drug-drug interaction and their implication in clinical management

C Palleria, A Di Paolo, C Giofrè, C Caglioti… - Journal of research in …, 2013 - ncbi.nlm.nih.gov
Drug-drug interactions (DDIs) are one of the commonest causes of medication error in
developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20 …

ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert …

WS Aronow, JL Fleg, CJ Pepine, NT Artinian, G Bakris… - Circulation, 2011 - Am Heart Assoc
This document was written with the intent to be a complete reference at the time of
publication on the topic of managing hypertension in the elderly. Given the length of the …

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): position statement and 10 recommendations for action

D Mangin, G Bahat, BA Golomb, LH Mallery… - Drugs & aging, 2018 - Springer
Globally, the number of drug prescriptions is increasing causing more adverse drug events,
which is now a significant cause of mortality, morbidity, and disability that has reached …