[HTML][HTML] The Role of TNF-α in Alzheimer's Disease: A Narrative Review

D Plantone, M Pardini, D Righi, C Manco, BM Colombo… - Cells, 2023 - mdpi.com
This review analyzes the role of TNF-α and its increase in biological fluids in mild cognitive
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …

[HTML][HTML] Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration: from oxidative stress to …

R Iorio, G Celenza, S Petricca - Antioxidants, 2022 - mdpi.com
Inflammation and oxidative stress are interlinked and interdependent processes involved in
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …

[HTML][HTML] Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration

I Ballasch, E García-García, C Vila… - Brain, behavior, and …, 2023 - Elsevier
In the last two decades, microglia have emerged as key contributors to disease progression
in many neurological disorders, not only by exerting their classical immunological functions …

A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease

HS Sardou, PR Vosough, M Abbaspour, A Akhgari… - …, 2023 - Springer
Synthetic drugs and monoclonal antibodies are the typical treatments to combat
inflammatory bowel disease (IBD). However, side effects are present when these treatments …

Superoxide dismutase: a key target for the neuroprotective effects of curcumin

D Khayatan, SM Razavi, ZN Arab, Y Hosseini… - Molecular and Cellular …, 2024 - Springer
Over the past few years, the prevalence of neurodegenerative diseases (NDD) has
increased dramatically. The community health system is burdened by the high healthcare …

[HTML][HTML] The effect of Ni gella sativa and vitamin D3 supplementation on the clinical outcome in COVID-19 patients: A randomized controlled clinical trial

SA Said, A Abdulbaset, AA El-Kholy… - Frontiers in …, 2022 - frontiersin.org
Background: The coronavirus disease 2019 (COVID-19) is a novel coronavirus that causes
severe infection in the respiratory system. Since the immune status plays an essential role in …

[HTML][HTML] Anti-Neuroinflammatory Effects of Adaptogens: A Mini-Review

D Wróbel-Biedrawa, I Podolak - Molecules, 2024 - mdpi.com
Introduction: Adaptogens are a group of plants that exhibit complex, nonspecific effects on
the human body, increasing its ability to adapt, develop resilience, and survive in stress …

[HTML][HTML] Neuroinflammation in parkinson's disease and its treatment opportunities

E Çınar, BC Tel, G Şahin - Balkan medical journal, 2022 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a complex, chronic, and progressive neurodegenerative
disease that is characterized by irreversible dopaminergic neuronal loss in the substantia …

[HTML][HTML] Resveratrol activates antioxidant protective mechanisms in cellular models of Alzheimer's disease inflammation

C Bartra, Y Yuan, K Vuraić, H Valdés-Quiroz… - Antioxidants, 2024 - mdpi.com
Resveratrol is a natural phenolic compound with known benefits against
neurodegeneration. We analyzed in vitro the protective mechanisms of resveratrol against …

[HTML][HTML] Rational Design of Multifunctional Ferulic Acid Derivatives Aimed for Alzheimer's and Parkinson's Diseases

EG Guzmán-López, M Reina, LF Hernández-Ayala… - Antioxidants, 2023 - mdpi.com
Ferulic acid has numerous beneficial effects on human health, which are frequently
attributed to its antioxidant behavior. In this report, many of them are reviewed, and 185 new …